[HTML][HTML] Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways

H Kheraldine, I Gupta, H Alhussain, A Jabeen… - Computational and …, 2021 - Elsevier
… GAPDH was used as a control for the loaded amount of the … dendrimers on HER2-positive
human breast cancer cell lines (… line models, we investigated the downstream target of HER1 …

Nanotechnology of tyrosine kinase inhibitors in cancer therapy: A perspective

E Russo, A Spallarossa, B Tasso, C Villa… - International Journal of …, 2021 - mdpi.com
tumor cell surface properties, recognized as active targeting. … Some types of dendrimers
exhibit inorganic elements as … The new Sorafenib-loaded targeted NPs efficiently delivered …

In vitro/vivo antitumor study of modified-chitosan/carboxymethyl chitosan “boosted” charge-reversal nanoformulation

L Li, P Zhang, C Li, Y Guo, K Sun - Carbohydrate Polymers, 2021 - Elsevier
… The ideal anticancer nanoformulations for tumor-targeted … exerted to kill the tumor cells and
inhibit the tumor growth. However, … However, cationic PAMAM dendrimers could be rapidly …

Biomaterial-mediated exogenous facile coating of natural killer cells for enhancing anticancer efficacy toward hepatocellular carcinoma

AK Jangid, S Kim, HJ Kim, K Kim - Bioconjugate Chemistry, 2023 - ACS Publications
… Clicking on the donut icon will load a page at altmetric.com … , and (3) lactobionic acid (LBA)
for cancer recognition. The … between engineered NK cells and target liver cancer cells, and …

Developing actively targeted nanoparticles to fight cancer: Focus on Italian research

M Argenziano, S Arpicco, P Brusa, R Cavalli, D Chirio… - Pharmaceutics, 2021 - mdpi.com
… G(4)-PAMAM dendrimer has also been linked to lactobionic … and loading with sorafenib,
targeted dendrimers displayed higher … receptor-expressing human liver-cancer cell line, HepG-2, …

The pharmaceutical technology approach on imaging innovations from Italian research

G Ailuno, RM Iacobazzi, A Lopalco, S Baldassari… - Pharmaceutics, 2021 - mdpi.com
… drug sorafenib, which is able to targethuman liver cancer cells, characterized by undetectable
level of receptor, confirmed the targeting specificity of Ac-La-G(4)-PAMAM-FITC dendrimer

Polymeric biomaterial-inspired cell surface modulation for the development of novel anticancer therapeutics

AK Jangid, S Kim, K Kim - Biomaterials Research, 2023 - spj.science.org
… -based cancer recognition moieties, ie, folic acid, lactobionictargeting cancer cell binding
and the treatment of tumor cells. … Fe 3 O 4 @PDA loaded NK cells also pointedly reduced the …

Novel drug delivery systems for loading of natural plant extracts and their biomedical applications

HS Rahman, HH Othman, NI Hammadi… - International journal …, 2020 - Taylor & Francis
… Citation116 Thus, this dendrimer can offer to target ligands to … -targeting carrier was
developed that showed high cellular uptake in αvβ3 integrin-positive HepG2 liver carcinoma cells, …

Microfluidic preparation and in vitro evaluation of iRGD-functionalized solid lipid nanoparticles for targeted delivery of paclitaxel to tumor cells

I Arduino, Z Liu, RM Iacobazzi, AA Lopedota… - International Journal of …, 2021 - Elsevier
… A tumor homing peptide, iRGD, owning a cryptic C-end Rule (CendR) motif is responsible
… extravasation and tumor penetration of the peptide. In this study, the Paclitaxel loaded-SLNs …

Application of nanoparticles in drug delivery for the treatment of osteosarcoma: focussing on the liposomes

W Liang, Y Dong, R Shao, S Zhang, X Wu… - … of Drug Targeting, 2022 - Taylor & Francis
… alendronate for targeting and guiding NPs towards the bone cancer cells. CDDP-loaded NPs
… The triazine-modified dendrimer also effectively induces apoptosis of OS cells in vitro and …