[HTML][HTML] Clinical applicability of renin-angiotensin system inhibitors in cancer treatment

H Jiang, Z Tai, Z Chen, Q Zhu, L Bao - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
… for new treatment strategy, such as targeted therapy, immunotherapy, and … effect in the
treatment of cancer, RASi can also reduce the side effects of molecular targeted therapy in cancer

Evaluating the benefits of renin-angiotensin system inhibitors as cancer treatments

MV Perini, RS Dmello, TL Nero, AL Chand - Pharmacology & therapeutics, 2020 - Elsevier
… -classical roles in cancer, the notion of repurposing this class of medications as cancer
treatment(s) … Pharmacological targeting of the AT1R and ACE has been extremely effective in the …

[HTML][HTML] The role of the renin-angiotensin system inhibitors in malignancy: a review

J Yang, X Yang, L Gao, J Zhang, C Yi… - … journal of cancer …, 2021 - ncbi.nlm.nih.gov
… to enhance the effect of chemo-radiotherapy and targetedtreatment (chemo-radiotherapy
and targeted therapy). In the … of using RASi to enhance cancer treatment efficacy but also point …

ReninAngiotensin System in the Tumor Microenvironment

K Nakamura, R Okuyama, Y Kawakami - Tumor Microenvironment …, 2020 - Springer
… A high neutrophil-to-lymphocyte ratio has been shown to be associated with a poor treatment
effect of immunotherapy [49, 50]. In a model of pancreatic cancer, ARB administration was …

Renin-angiotensin system in lung tumor and microenvironment interactions

MJ Catarata, R Ribeiro, MJ Oliveira, C Robalo Cordeiro… - Cancers, 2020 - mdpi.com
… Contrary to the Ang II effect in tumor immunity response, interesting findings also … that
targeting RAS could alleviate immunosuppression and enhance the outcome of immunotherapy. …

[HTML][HTML] Reninangiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors

ZD Drobni, O Michielin, T Quinaglia, DA Zlotoff… - … Journal of Cancer, 2022 - Elsevier
… reached statistical significance for gastrointestinal cancer (multivariable … therapy suggest
potential synergy between VEGF-targetedCancer immunotherapy using checkpoint blockade …

Breast cancer and the renin-angiotensin system (RAS): Therapeutic approaches and related metabolic diseases

FS de Miranda, JPT Guimarães… - Molecular and Cellular …, 2021 - Elsevier
target (Schietinger et al., 2008). In fact, immunotherapy has revolutionized cancer treatment
and … and other diseases as side effect of radiation therapy by lowering the dose of irradiation. …

The role of the reninangiotensin system in the cancer stem cell niche

EJ Kilmister, ST Tan - Journal of Histochemistry & …, 2021 - journals.sagepub.com
immunotherapies, such as chimeric antigen receptor T-cell therapy, and (4) immune checkpoint
blockers targeting … This study also shows the effect of RASIs is dependent on the cancer

Impact of renin-angiotensin system inhibitors on outcomes in patients with metastatic renal cell carcinoma treated with immune-checkpoint inhibitors

PV Nuzzo, E Adib, N Weise, C Curran, T Stewart… - … genitourinary cancer, 2022 - Elsevier
… or treated with ICI in combination with VEGF-targeted therapy … The additive effect of RASi
on systemic treatment in cancer … In mRCC, RASi improved survival in mRCC patients treated

The Potential Therapeutic Value of Renin-Angiotensin System Inhibitors in the Treatment of Colorectal Cancer

E Tabatabai, M Khazaei, MR Parizadeh… - Current …, 2022 - ingentaconnect.com
… to improve the efficacy and selectivity of current and future anticancer strategies targeting
renin-angiotensin systems. … significance of ACE2 and Mas receptor in human colon adenocar…