… for various types of cancer like breast, ovarian, lung cancers etc. The … leads to cell cycle arrest,
and eventually cell apoptosis. In … hence was said to be critical for Taxol-induced cell death. …

… Despite these reports, the precise mechanism of taxol-induced apoptosis remains poorly … )
and upregulate the tumor suppressor protein, P53 (34). Cell cycle arrest and apoptosis are the …

… Further experiments showed that paclitaxel caused mitotic catastrophe, cell cycle arrest of …
of cancer, including AIDS-related Kaposi sarcoma, breast cancer, non-small cell lung cancer …

… HDAC inhibitors induce cell cycle arrest and apoptosis via up-regulation of p21 and caspase
activation by inhibiting HDAC activity. TSA (an HDAC inhibitor) and PTX synergistically …

… types of cancers, such as breast, ovarian, lung cancers, in … Taxol-prompted M-phase cell
cycle arrest and cell death are … Taxol-induced apoptosis is directly linked to the influence on …

… Thereby, a wide range of potential cell fates are possible such as death by apoptosis or
necrosis, as well as induction of a permanent cell cycle arrest (senescence). After repeated …

… in lung tumor cells. In total, 94.4% of AA-PEG-exoPTX were co-localized with lung metastases
… suppressor genes (TSGs) are essential genes related to cell division, apoptosis, and DNA …

… that inhibits microtubule disassembly, resulting in cell cycle arrest in late G2 and M phases.
… in Taxol-induced apoptosis has been shown using glutathione depletion in cancer cells [7]. …

… expression that affects apoptosis. In summary, we have demonstrated the synergistic effect
of taxanes enhancing TRAIL-mediated apoptosis in two different prostate cancer cells via ER …

… cells cannot occur properly, which results in cell cycle arrest followed by some type of
programmed cell death, in most cases apoptosis. … non-small cell lung cancer (NSCLC) cells A549, …