In a more-than-human world of design and designing, outcomes and experiences are the result of a sustained yet more uncertain interplay between people and networked computational things—as well as directly between these things in themselves. Developing new design methodologies and tools to unlock the potentials of technologies such as Big Data, the Internet of Things, Machine Learning, and Artificial Intelligence for the everyday job of design is necessary but not sufficient. There is now a need to fundamentally question human-centered design and raise critical questions about the way we design.