Neuroimmune interactions in painful TMD: mechanisms and treatment implications

Y Yi, X Zhou, X Xiong, J Wang - Journal of Leukocyte Biology, 2021 - academic.oup.com
… of temporomandibular joint (TMJ), and neurogenic … to neuron excitability amplification, leading
to pain sensitization, … increased in the trigeminal ganglia over the OA chronic pain period. …

… Prevents Suppression of GABAergic Protein Expression in Female Sprague Dawley Trigeminal Ganglion in a Model of Chronic Temporomandibular Joint Disorder

SR Antonopoulos, DA Garten, PL Durham - Archives of Oral Biology, 2024 - Elsevier
excitability, were significantly decreased on day 14 post jaw … within the dorsal root ganglion
alleviated hypersensitivity to … , it is likely that GSE could potentiate the effect of baclofen by …

Estrogen status and trigeminal ganglion responses to jaw movement

X Zhang, M Rahman… - Journal of dental …, 2022 - journals.sagepub.com
… mild tissue inflammation and estrogen status influenced the responses of trigeminal ganglion
neurons to jaw palpation or jaw … Chronic temporomandibular joint disorders (TMDs) are …

… occlusal interference-induced chronic masseter hyperalgesia by increasing the neuronal excitability and TRPV1 function of trigeminal ganglion in ovariectomized rats

Y Liu, XX Xu, Y Cao, SY Mo, SS Bai, YY Fan… - International Journal of …, 2021 - mdpi.com
… of the masticatory muscles and/or temporomandibular joints (… expression levels in the dorsal
root ganglion (DRG) in mice [… that neuronal excitability was rapidly potentiated. Although this …

[HTML][HTML] Increased substance P and synaptic remodeling occur in the trigeminal sensory system with sustained osteoarthritic temporomandibular joint sensitivity

MM Sperry, EJ Granquist, BA Winkelstein - Pain Reports, 2021 - journals.lww.com
… loading alters expression of proteins associated with neuronal excitability in the Sp5C and …
is linked to long-term synaptic potentiation in secondary neurons, 13 synaptic remodeling was …

Pulpitis pain relief by modulating sodium channels in trigeminal ganglia

KH Lee - Journal of Korean society of Dental Hygiene, 2024 - koreascience.kr
potentiation with central sensitization [14,15]. In coincide with our previous in vitro study [11],
we observed the neuronal hyper-excitability and … temporomandibular joint. The depolarizing …

Pain management and rehabilitation for central sensitization in temporomandibular disorders: a comprehensive review

M Ferrillo, A Giudice, N Marotta, F Fortunato… - International Journal of …, 2022 - mdpi.com
… masticatory muscles and temporomandibular joints (TMJ). In … subnucleus in patients with
chronic trigeminal pain. In short, this … produces a transient dysfunction of nerve excitability at the …

NMDARs mediate peripheral and central sensitization contributing to chronic orofacial pain

YJ Liu, YL Li, ZH Fang, HL Liao, YY Zhang… - Frontiers in Cellular …, 2022 - frontiersin.org
pain have been diagnosed with temporomandibular joint … in turn modulates cell membrane
excitability and enhances … through activation of Fyn and potentiate NR2B-containing NMDAR-…

Plastic changes in nociceptive pathways contributing to persistent orofacial pain

M Shinoda, S Hitomi, K Iwata, Y Hayashi - Journal of Oral Biosciences, 2022 - Elsevier
… for pathological orofacial pain such as temporomandibular joint dysfunction, myofascial …
trigeminal nerve injury potentiates TG neuronal excitability, thereby causing orofacial pain

Dynorphin Promotes Comorbid Migraine-like Pain in Female Mice with Temporomandibular Joint Disorders

H Shu - 2020 - oaktrust.library.tamu.edu
… MMTL injury causes inflammatory reaction in the ligated tendon and neuronal activation
in the spinal trigeminal nucleus (Sp5C) ................................... 16 2.3.2 MMTL injury produces a …