… Modern Mass Spectrometry Can Solve Ancient Questions: A Multi-Omics Study of the Stomach Content of the Oldest Human Ice Mummy, the 5300-Year-Old Iceman …

R Grimm - Proteomic Profiling: Methods and Protocols, 2021 - Springer
… This is of great interest as Helicobacter pylori (H. pylori) was detected in the Iceman’s
stomach, and the entire DNA sequence of this ancient form of H. …

Ötzi, the iceman–lessons from modern mummy research

A Zink - 2023 - tobias-lib.ub.uni-tuebingen.de
… strain revealed a surprising result, as the 5,300-year-old bacterium matched to the modern …
and genome reconstruction revealed not only that the ancient Helicobacter pylori strain was a …

The Helicobacter pylori genome evolution in different gastric cancer risk Colombian populations

K Guzman, L Montenegro, A Pazos - 2021 - researchsquare.com
… The 5300-year-old Helicobacter pylori genome of the Iceman. Science. 2016;351:162–165. …
Helicobacter pylori genomic microevolution during naturally occurring transmission between …

Helicobacter pylori's historical journey through Siberia and the Americas

Y Moodley, A Brunelli, S Ghirotto… - Proceedings of the …, 2021 - National Acad Sciences
… on genetic diversity within Helicobacter pylori, a bacterium that infects 50% of all humans. H.
… We also extended these studies with higher resolution genomic short-read sequencing for a …

Phylogenetic structure of the global population of Helicobacter Pylori

DA Starkova, AV Svarval - Russian Journal of Infection and Immunity, 2022 - iimmun.ru
… rate of mutation and recombination events led to extremely high genomic polymorphism of
the H. … An African origin for the intimate association between humans and Helicobacter pylori. …

Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations

HA Thorpe, E Tourrette, K Yahara, FF Vale… - Nature …, 2022 - nature.com
pylori genome sequences shows a phylogeographic pattern similar to that of its host, … pylori
genome of the Tirolian Iceman, Ötzi, which has an ancestry profile like that found in modern …

Pathogenomics of Helicobacter pylori

Y Yamaoka, B Saruuljavkhlan, RI Alfaray… - Helicobacter pylori and …, 2024 - Springer
… The first genome of a Helicobacter pylori strain was published in the year 1997, the … and
reconstruction of the 5,300-year-old H. pylori genome of Ötzi the Iceman (Maixner et al. 2016, …

Evolutionary medicine perspectives: Helicobacter pylori, lactose intolerance, and 3 hypotheses for functional and inflammatory gastrointestinal and hepatobiliary …

GI Leontiadis, GF Longstreth - … journal of the American College of …, 2022 - journals.lww.com
… inflammatory and carcinogenic variability of Helicobacter pylori. Antibiotic-resistant
strains … be a biomarker;(ii) the thrifty gene hypothesis proposes genetic adaptation to feast–famine …

Helicobacter pylori infection causes both protective and deleterious effects in human health and disease

AK Miller, SM Williams - Genes & Immunity, 2021 - nature.com
… The H. pylori genome is highly plastic, and a study of 1 531 genes showed that as many as
25… pylori gene expression and showed increased expression of SabA in those with IDA [63]. …

History of Ancient DNA Analysis in Mummy Research

JH Hong, CS Oh, DH Shin - The Handbook of Mummy Studies: New …, 2021 - Springer
… ) can yield genetic information (eg, Helicobacter pylori) that cannot be obtained simply from
… Ötzi the Iceman and were able to retrieve a 5300-year-old H. pylori genome. Metagenomic …