Histone binding of ASF1 is required for fruiting body development but not for genome stability in the filamentous fungus Sordaria macrospora

J Breuer, T Busche, J Kalinowski, M Nowrousian - Mbio, 2024 - Am Soc Microbiol
… The highly conserved eukaryotic histone chaperone ASF1 is … After proximity ligation, the
cross-links were reversed at 68C … shown to be essential for ASF1-histone binding in yeast (19). …

Molecular Basis for Chaperone Control of Rtt109 Acetylation of Histone H3-H4

N Akhavantabib - 2021 - utd-ir.tdl.org
… Vps75 and Asf1 are the two known histone chaperones that … the Nap-family of histone
chaperones in yeast. This family is … negative Cterminal tail of Vps75 and the positive N-terminal

Structural insights into histone chaperone Asf1 and its characterization from Plasmodium falciparum

DK Srivastava, S Gunjan, C Das, V Seshadri… - Biochemical …, 2021 - portlandpress.com
… , which promotes the histone H3/H4 interaction. Likewise, PfAsf1 also contains a poly-asparagine
rich … To identify how Plasmodium Asf1 is similar to yeast and human histone chaperone

[HTML][HTML] Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

B Simon, HJ Lou, C Huet-Calderwood, G Shi… - Nature …, 2022 - nature.com
… In yeast, the Asf1 C-terminal tail is highly enriched in acidic … a > 200-fold reduction in histone
H3–H4 binding affinity 26 . The … Histone deficiency enhances phosphorylation of ASF1 by …

[PDF][PDF] Why are histones dynamic?

R Loewith, M Strubin - access.archive-ouverte.unige.ch
… This process is called histone turnover and is promoted by a … Asf1 as a histone chaperone
was first suggested by a yeast … This requires that formaldehyde not only rapidly cross-links DNA…

[HTML][HTML] The replisome guides nucleosome assembly during DNA replication

W Zhang, J Feng, Q Li - Cell & bioscience, 2020 - Springer
… –H4 and promote histone chaperone-mediated RC … Yeast RFC was found to bind the histone
chaperone Asf1 in vitro, and the N-terminal of Asf1 contributes to the interaction of Asf1 with …

[HTML][HTML] Genome protection: histone H4 and beyond

K Kumar, R Moirangthem, R Kaur - Current genetics, 2020 - Springer
… reduced histone H4 gene dosage in the pathogenic yeast Candida … The C-terminal H4 tail
also interacts with Asf1 chaperone, … glabrata H4 interacts with histone chaperones, and/or the …

[HTML][HTML] Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S

…, C Ruan, Y Ou, B Peng, X Zheng, J Lei, B Li, C Yan… - Nature, 2023 - nature.com
Histone H3K36me3 promotes the deacetylase activity of the … of PHD1-guided H3 deacetylation
by Rpd3S in yeast, we used a … Rtt109, in partnership with histone chaperones Asf1 and …

[PDF][PDF] Wss1 promotes replication stress tolerance by degrading histones

K Maddi, DK Sam, F Bonn, S Prgomet, E Tulowetzke… - Cell reports, 2020 - cell.com
… However, the fact that histones are essential for yeast … During S phase, histone chaperones
sequester histones and deposit … The histone H3 chaperone, Asf1, was shown to buffer excess …

[HTML][HTML] A novel SNF2 ATPase complex in Trypanosoma brucei with a role in H2A.Z-mediated chromatin remodelling

T Vellmer, L Hartleb, A Fradera Sola, S Kramer… - PLoS …, 2022 - journals.plos.org
… Z can block Notch and ΔNp63a target genes but promotes … In yeast, the YEATS domain
of Yaf-9 is essential for histoneCross-links were reversed at 65C for ~16 h in the presence …