… uses allelic exchange plasmids, which is a multistep and overall inefficient process. Better
gene … glutamicum genome editing through optimized expression of guide RNA and Cas9 and …

… Corynebacterium glutamicum has been considered a promising synthetic biological
platform for biomanufacturing and bioremediation. However, there are still some challenges in …

Corynebacterium glutamicum, a gram-positive and facultative anaerobic bacterium, is
widely used for the industrial production of amino acids, such as l-glutamate and l-lysine. C. …

… Corynebacterium glutamicum, a GRAS strain accumulated … in 1956, providing a feasible
process for the fermentative production of amino … glutamicum harboring the sacC gene from M. …

… belongs to the microbes of enormous biotechnological … A deep understanding of the
biochemical processes in C. … function becomes more apparent when looking at the effects of …

… in the field of industrial and environmental biotechnology (… procedures, have been used
to introduce mutations into the … glutamicum R genome consists of a circular 3 314 179 bp …

… process of Corynebacterium glutamicum producing L-lysine. … -lysine, its expression
directly affects the efficiency of product … of the global factor encoding gene lrp. At present, …

… through gene editing (Fig. 2), and a series of methods have been developed for C. … used
as a production host of aromatic compounds involved in biotechnology [69, 93]. At present, …

… in industrial white biotechnology. It has been widely applied in the producing processes of
amino … glutamicum genome, the Cas9 with a GC-rich PAM sequence was more attractive in C. …

… Cgl2467 has the activity of acetaldehyde dehydrogenase, and we analyzed the effects of
residue … Simultaneously interfering with multiple processes that maintain genome stability is an …