… details of NLRP3 inflammasome activation with a … regulation of the NLRP3 inflammasome
machinery. We also present a detailed summary of multiple positive and/or negative regulatory …

… A priming signal is required before a subsequent signal activates the NLRP3 inflammasome.
… , IL-1β or TNFα, which activates NF-κB, leading to the upregulation of NLRP3 and IL-1β [ …

… , and the pharmacological approaches that target the inflammasome for therapeutic …
considered central organelles in regulating the NLRP3 inflammasome activation. Mitochondria can …

… of NLRP3 inflammasome activation, how dysregulation of NLRP3 inflammasome activation
causes disease, and potential therapeutics that inhibit NLRP3 inflammasome activation. …

… NLRP3 inflammasome activation and cell death and discuss potential therapeutics that target
cell death effectors in NLRP3 … on the regulation of NLRP3 inflammasome activation by cell …

… NLRP3 inflammasome activation pathway. Second, we review the cellular/molecular
mechanisms of NLRP3 inflammasome activation … involvement of the NLRP3 inflammasome in the …

… recent efforts to develop therapeutic applications targeting the NLRP3 inflammasome to cure
and … NLRP3 inflammasome-related diseases and current development of small molecule …

… activation and regulation. We also summarize recent studies that have reported on the roles
of NLRP3 inflammasome in … and NLRP3 inflammasome, can be used as a therapeutic target. …

… targeting to the inflammasome. We therefore in this review focus … of NLRP3 inflammasome
activation and its regulatory signaling … therapeutic drugs targeting NLRP3 inflammasome. …

… a detailed summary of NLRP3 inflammasome activation (and … the therapeutic potential of
targeting NLRP3 for cancer therapy, emphasizing how understanding NLRP3 inflammasome-…