Imbalanced serum levels of resolvin E1 (RvE1) and leukotriene B4 (LTB4) in patients with allergic rhinitis

R Lotfi, A Davoodi, SH Mortazavi, A Gorgin Karaji… - Molecular biology …, 2020 - Springer
… of pro-inflammatory leukotriene B4 (LTB4), anti-inflammatory … of inflammatory disorders were
selected as the control group. … roles of the LTB4-BLT1 pathway in the recruitment of allergen-…

[HTML][HTML] PPARs as key mediators in the regulation of metabolism and inflammation

M Vázquez-Carrera, W Wahli - International Journal of Molecular …, 2022 - mdpi.com
… in 1996 linking PPARα to the control of inflammation [13], the anti-inflammatory role of this
… [14] discussed the interplay of PPARα with different pathways in inflammation, transcription, …

[HTML][HTML] The role of PPAR alpha in the modulation of innate immunity

M Grabacka, M Pierzchalska, PM Płonka… - International Journal of …, 2021 - mdpi.com
… to PPARα and other pathways, (ii) cross-coupling of the PPARα/… involves the catabolism of
lipid mediators, such as leukotrienePPARα signaling contributes to inflammatory pain control

Relationship between Natural Activators of Peroxisome Proliferator Activated Receptors (PPARs) and Endothelial Dysfunction in Patients with Peripheral and …

MS Abou-Taleb, NM Assem… - American Journal of …, 2021 - search.ebscohost.com
… Its reaction is inflammatory at the wall of vessels in response … Plasma level of leukotriene
B4 (LTB4) in the control and … is found via 5-lipoxygenase pathway. LTB4 helps stimulating …

[HTML][HTML] Root canal contamination or exposure to lipopolysaccharide differentially modulate prostaglandin E 2 and leukotriene B 4 signaling in apical periodontitis

FWG Paula-Silva, FR Ribeiro-Santos… - Journal of Applied Oral …, 2020 - SciELO Brasil
… for the lipid mediators prostaglandin E2 and leukotriene B4. … PPARα, PPARδ and PPARγ
receptors are activated by … in inflammation, an investigation of two important pathways of …

Peroxisome Proliferator‐Activated Receptors as a Therapeutic Target in Asthma

OY Kytikova, JM Perelman, TP Novgorodtseva… - PPAR …, 2020 - Wiley Online Library
… of strategies to control the activity of the inflammatory process [5, … PPARα can induce the
production of anti-inflammatory … RvE1 receptors include leukotriene B4 receptor 1 (BLT1) and G …

Leukotrienes in innate immunity: still underappreciated after all these years?

CH Serezani, M Divangahi… - The Journal of …, 2023 - journals.aai.org
… during either infectious or noninfectious inflammation leads to BLT1-… pathways promote
robust cytokine generation and signaling that contribute to exaggerated tissue inflammation

[PDF][PDF] Polyunsaturated fatty acids and lipid mediators controlling chronic inflammation in asthma

OY Kytikova, YK Denisenko, TP Novgorodtseva… - Russian Open Medical …, 2023 - romj.org
… and inhibit intracellular signaling pathways of inflammation. Lipid … PPARα reduces the
synthesis of proinflammatory mediators … Resolvin E1 reduces leukotriene B4-induced intracellular …

The role of peroxisome proliferator-activated receptors (PPAR) in immune responses

A Christofides, E Konstantinidou, C Jani, VA Boussiotis - Metabolism, 2021 - Elsevier
… evidence that PPARα might exert anti-inflammatory action by … via the SIRT1-dependent
signaling pathway [41,42]. … are implicated in the control of the inflammatory state of adipose tissue …

[HTML][HTML] Structural insights on ligand recognition at the human leukotriene B4 receptor 1

N Michaelian, A Sadybekov, É Besserer-Offroy… - Nature …, 2021 - nature.com
Leukotriene B4 (LTB4) is a pro-inflammatory lipid mediator … BLT1 regulates
inflammation-related processes such as … peroxisome proliferator-activated receptors PPARα 20 …