A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

HJ Kim, JS Park, SW Yi, M Go, HR Kim, SJ Lee… - Biomaterials …, 2020 - pubs.rsc.org
… PNts have the potential to serve as carriers of therapeutic … the capability of PNts to cross the
placenta was influenced by … In this study, the PNts crossed the placenta starting at the middle …

Nanoparticles induced embryo–fetal toxicity

Z Wang, Z Wang - Toxicology and Industrial Health, 2020 - journals.sagepub.com
Quantum dots (QDs), based on semiconductors of groups IV (… placenta, CNTs crossed
the placental barrier, influenced … The potential pathways of fetal toxicity induced by NPs in …

Breakthrough of ZrO2 nanoparticles into fetal brains depends on developmental stage of maternal placental barrier and fetal blood-brain-barrier

Z Wang, C Zhang, F Huang, X Liu, Z Wang… - Journal of Hazardous …, 2021 - Elsevier
… However, how such ingestion by pregnant mother influences … When nanoparticles crossed
the placental barrier and … potential toxicity of ZrO 2 NPs to placenta, we also measured the …

[HTML][HTML] Nanomedicines: An approach to treat placental insufficiency and the current challenges

CM Van Kammen, SJ van Woudenberg… - Journal of Controlled …, 2023 - Elsevier
… The others two studied classes, quantum dots and silicon … been shown to influence the
trans-placental passage. The few … the purpose of not passing the placental barrier will be too large …

Effects of QDs exposure on the reproductive and embryonic developmental toxicity in mice at various pregnancy stages

L Chen, F Zheng, P Yang, B Chen… - Toxicology …, 2020 - academic.oup.com
Quantum dots (QDs) have recently attracted considerable … across the placenta, which in turn
affected the ability of the … general toxicity indicators used for potentially toxic chemicals [24, …

Adverse reproductive and developmental consequences of quantum dots

Y Yao, Z Chen, T Zhang, M Tang - Environmental Research, 2022 - Elsevier
Crossing of the blood-testis barrier. Slow growth and … fetuses through the placental barrier
and caused dead pups. … that could have appeared to influence the work reported in this paper. …

Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies

E Bongaerts, TS Nawrot, T Van Pee, M Ameloot… - Particle and Fibre …, 2020 - Springer
… Such in utero exposure may not only influence fetal development and induce adverse …
towards and across the placenta in in vitro cellular barriers, ex vivo placental perfusion models, in …

The maternal-fetal transfer of passive immunity as a mechanism of transplacental nanoparticle drug delivery for prenatal therapies

WH Tse, S Higgins, D Patel, M Xing, AR West… - Biomaterials …, 2022 - pubs.rsc.org
… modifications) and material can impact the integrity of the placental epithelium and transfer
… as quantum dots, and silica, polystyrene, and titanium oxide NPs across the placenta was …

Biological applications and toxicity minimization of semiconductor quantum dots

S Filali, F Pirot, P Miossec - Trends in biotechnology, 2020 - cell.com
… The extraordinary potential of semiconductor quantum dots (QDs) has resulted in their …
of a strategy to control their toxicity for potential therapeutic applications. Here, we describe …

[HTML][HTML] Dynamic placenta-on-a-chip model for fetal risk assessment of nanoparticles intended to treat pregnancy-associated diseases

S Shojaei, MS Ali, M Suresh, T Upreti… - … et Biophysica Acta (BBA …, 2021 - Elsevier
placenta of mice presenting a potentialplacenta to the fetus, unlike the 519 nm particles
highlighting the effect of size as a key determinant influencing NP transport across the placenta […