… A PPHN animal model has been developed in fetal lambs by … The impact of midazolam
sorption on pharmacokinetics in … IV Other patients will appear fully conscious and might even be …

… vein and the sheep were premedicated with midazolam (Midazolam, … Alterations in the level
of consciousness are associated with … , the pharmacokinetics of alfentanil in sheep has been …

… Both can be given IV, but midazolam can also be given IM or SC … been based on
pharmacokinetic recommendations where set … use of alfentanil when infused at 60 mcg/kg/h. In …

… research into the pharmacokinetics and efficacy of local anaesthetics in sheep was carried
… [389] evaluated the safety of lumbar intrathecal midazolam in sheep. Doses of up to 15 mg/…

… The duration of action is longer than for morphine but is dependent on dose, administration
route, and outcome measure (nociceptive testing vs. indices of postoperative pain). Lately, …

… In the first part of this chapter, we review the pharmacokinetic … Midazolam is soluble in water
at low pH but its imidazole ring … the free fraction of alfentanil crossing the blood–brain barrier …

… N2O has some unique pharmacokinetic and pharmacodynamic … infusion of morphine, or
morphine plus dexmedetomidine in … Effect of alfentanil on the minimum alveolar concentration of …

… Plasma and urine pharmacokinetics of hydroxyzine and … the same CYP3A4 enzyme (eg
alfentanil), fail to demonstrate … than the original compound eg morphine glucuronide. Many of the …

… 2 ) in rats sedated with medetomidine, midazolam and fentanyl. The hypothesis was that
vatinoxan administration with medetomidine, midazolam and fentanyl would result in a faster …

… Much evidence suggests that both consciousness and … of brain concentrations of intravenous
anesthetics in sheep. … : Pharmacokinetic-pharmacodynamic modeling of midazolam effects …