[HTML][HTML] Surfactant replacement therapy: from biological basis to current clinical practice
R Hentschel, K Bohlin, A van Kaam, H Fuchs… - Pediatric …, 2020 - nature.com
… This review summarizes the current knowledge on the physiological action of endogenous
and exogenous pulmonary surfactant, the role of different types of animal-derived and …
and exogenous pulmonary surfactant, the role of different types of animal-derived and …
[HTML][HTML] A recipe for a good clinical pulmonary surfactant
J Pérez-Gil - biomedical journal, 2022 - Elsevier
… current concepts on the compositional and structural determinants defining pulmonary
surfactant … -derived or recombinant or synthetic therapeutic surfactants, as well as a the most …
surfactant … -derived or recombinant or synthetic therapeutic surfactants, as well as a the most …
[HTML][HTML] Structural hallmarks of lung surfactant: Lipid-protein interactions, membrane structure and future challenges
JC Castillo-Sánchez, A Cruz, J Pérez-Gil - Archives of biochemistry and …, 2021 - Elsevier
… Lung surfactant (LS) is an outstanding example of how a highly regulated and dynamic …
stabilizes the respiratory air-liquid interface in the mammalian lung. The present review dissects …
stabilizes the respiratory air-liquid interface in the mammalian lung. The present review dissects …
Pulmonary surfactant: a mighty thin film
F Possmayer, YY Zuo, RAW Veldhuizen… - Chemical …, 2023 - ACS Publications
… pulmonary surfactant… pulmonary surfactant stabilizes our alveoli has still not been achieved.
It has long been suggested (but not always accepted) that the ability of pulmonary surfactant …
It has long been suggested (but not always accepted) that the ability of pulmonary surfactant …
Recent progress on surfactant protein A: cellular function in lung and kidney disease development
SD King, SY Chen - American Journal of Physiology-Cell …, 2020 - journals.physiology.org
… In this mini-review, we discuss SP-A functions and the consequences of SP-A genetic
mutations or pulmonary surfactant deficiencies, with a specific emphasis on the recent progress in …
mutations or pulmonary surfactant deficiencies, with a specific emphasis on the recent progress in …
[HTML][HTML] The Past and Future of Genetics in Pulmonary Disease-You Can Teach an Old Dog New Tricks
LM Nogee, A Hamvas - Pediatric pulmonology, 2020 - ncbi.nlm.nih.gov
… As an example, genetic disorders of surfactant metabolism result … respiratory failure to adult
onset pulmonary fibrosis (1-7). The lung histopathology diagnoses associated with surfactant …
onset pulmonary fibrosis (1-7). The lung histopathology diagnoses associated with surfactant …
[HTML][HTML] Fluid Films as Models for Understanding the Impact of Inhaled Particles in Lung Surfactant Layers
E Guzmán - Coatings, 2022 - mdpi.com
… Once pollutants enter the alveolar cavity, they are deposited on the lung surfactant (LS) film,
altering their mechanical performance which increases the respiratory work and can induce …
altering their mechanical performance which increases the respiratory work and can induce …
[HTML][HTML] Engineering of pulmonary surfactant corona on inhaled nanoparticles to operate in the lung system
… lung tissue results in the adsorption of pulmonary surfactant (… phospholipids (PLs) and
surfactant proteins (SPs) provides NPs … in lung environment. First, the physiological barriers in the …
surfactant proteins (SPs) provides NPs … in lung environment. First, the physiological barriers in the …
[HTML][HTML] Alveolar lipids in pulmonary disease. A review
CW Agudelo, G Samaha, I Garcia-Arcos - Lipids in health and disease, 2020 - Springer
… In vitro and ex vivo experiments with clinically used surfactant and with simplified model
phospholipid mixtures have shown the coexistence of two domains in the pulmonary surfactant …
phospholipid mixtures have shown the coexistence of two domains in the pulmonary surfactant …
[HTML][HTML] Alternative lung cell model systems for toxicology testing strategies: Current knowledge and future outlook
JA Moura, K Meldrum, SH Doak, MJD Clift - … Cell & Developmental Biology, 2023 - Elsevier
… towards the lung’s defense, as well as being important components of lung surfactant [9]. In
… lamellar bodies which contain and secrete lung surfactant (surfactant proteins A, B, and D) […
… lamellar bodies which contain and secrete lung surfactant (surfactant proteins A, B, and D) […