… Pyruvate as sole substrate in the medium could support blastocyst … during the first 48 h of
culture, between the one-cell and three-four-cell stages. … of random-bred 1-cell mouse embryos …

… ) led to a rapid increase in the blastocyst formation rate 46 . … the embryo development, but
this substrate is necessary for … mR1ECM, and M16 with different energy substrates) for NMR’…

… energy substrate is one of the most significant elements in any culture medium for optimum
embryo growth … to increase when supplementing the maturation media with 1.25 mM fructose …

… , that can improve in vitro embryo development rates, as well … regarding the specific substrate
requirements of each species. … might result from inadequate energy production, as studies …

… pathway in the presence of other energy sources. However, … to improve development to the
blastocyst stage and increase the … a delay of about one cell division to the blastocyst stage …

… ] and successfully increases embryonic development in hamster … is capable of transferring
this energy substrate, as well as its … oocytes was investigated to increase when supplementing …

… We proposed an increase in system N activity at the 4- to 8-… hyperosmotic as development
proceeds from the one-cell to the … While initially it seemed that both types of substrates were …

… In vitro studies indicate that exogenous energy substrates … inbred and random-bred strains
underwent a 2-cell block in … that substantial increases in embryo development will come from …

… two functions: to provide the energy sources required by the … the TCA metabolites have
different dynamic properties. Those … substrates improves development of one-cell random-bred …

… to the elimination of energy substrates but not to changes in … responding to minor increases
in pyruvate but cold stress did … to develop and underwent growth arrest at the one-cell stage…