Genome-wide DNA methylation dynamics during epigenetic reprogramming in the porcine germline

I Gómez-Redondo, B Planells, S Cánovas, E Ivanova… - Clinical …, 2021 - Springer
methylation reprogramming in pig germ cells follows the general dynamics shown in mice
and the second, occurring in the germline, is when primordial germ cells (PGCs) migrate to the …

Epigenetic Reprogramming in Mice and Humans: From Fertilization to Primordial Germ Cell Development

A Singh, DA Rappolee, DM Ruden - Cells, 2023 - mdpi.com
… However, its functional role is specialized and not required for the genome-wide gain of DNA
methylation [179]. H3K9me2’s specific functions in the post-implantation embryo in humans …

The dynamic chromatin landscape and mechanisms of DNA methylation during mouse germ cell development

K Shirane - Genes & Genetic Systems, 2022 - jstage.jst.go.jp
genome-wide mapping of both DNAme and histone post-translational modifications (PTMs)
in rare cell populations including developing germ cells. … is erased in primordial germ cells (…

The dynamics of DNA methylation during epigenetic reprogramming of primordial germ cells in medaka (Oryzias latipes)

X Wang, RK Bhandari - Epigenetics, 2020 - Taylor & Francis
… a systematic study of genome-wide DNA methylation dynamics across key stages of PGC …
which epigenetic reprogramming occurs in medaka fish, elucidating dynamics of genome DNA

Developmental alterations in DNA methylation during gametogenesis from primordial germ cells to sperm

MB Maamar, D Beck, E Nilsson, JR McCarrey… - IScience, 2022 - cell.com
… hypothesis was tested that DNA methylation alterations are dynamic and continually change
… stage-specific DNA methylation during gametogenesis from primordial germ cells (PGCs) to …

[HTML][HTML] EED is required for mouse primordial germ cell differentiation in the embryonic gonad

MG Lowe, MR Yen, FM Hsu, L Hosohama, Z Hu… - Developmental cell, 2022 - cell.com
… Integrating chromatin and whole genome bisulfite sequencing of epiblast and PGCs, we
identified a poised repressive signature of H3K27me3/DNA methylation that we propose is …

DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells

K Toriyama, WK Au Yeung, A Inoue, K Kurimoto… - BMC genomics, 2024 - Springer
… (PGCs) as part of the epigenetic reprogramming important for … in mouse PGCs and oocytes
and encodes a factor essential for female fertility. It prevents excessive DNA methylation in …

Long‐term expansion with germline potential of human primordial germ cell‐like cells in vitro

Y Murase, Y Yabuta, H Ohta, C Yamashiro… - The EMBO …, 2020 - embopress.org
… During expansion, hPGCLCs maintain an early hPGC-like transcriptome and preserve
their genome-wide DNA methylation profiles, most likely due to retention of maintenance …

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development

R Yan, X Cheng, C Gu, Y Xu, X Long, J Zhai, F Sun… - Nature Genetics, 2023 - nature.com
… participates in genome-wide methylation reprogramming remains … landscapes in mouse
early embryos and germ cells with … of Nlrp in mouse zygotic DNA methylation reprogramming. …

Genome-wide assessment of DNA methylation alterations induced by superovulation, sexual immaturity and in vitro follicle growth in mouse blastocysts

L Saucedo-Cuevas, E Ivanova, AC Herta, F Krueger… - Clinical …, 2023 - Springer
DNA methylation in embryos following ovarian stimulation is needed. Here, we provide
genome-wide DNA methylation … of prepubertal or adult mice, compared with blastocysts derived …