Cilia in the developing zebrafish ear
TT Whitfield - … Transactions of the Royal Society B, 2020 - royalsocietypublishing.org
… as a result of mutation in a gene coding for a dynein arm pre-assembly factor [45]. As in
zebrafish, this argues against an essential requirement for ciliary motility in otolith formation in …
zebrafish, this argues against an essential requirement for ciliary motility in otolith formation in …
The role of motile cilia in the development and physiology of the nervous system
C Ringers, EW Olstad… - … Transactions of the …, 2020 - royalsocietypublishing.org
… Ciliary motility is driven by axonemal dyneins, which create … cells, that bear primary cilia
capable of tethering the otolith (blue). … Ciliary motility is essential for the straightening of the body …
capable of tethering the otolith (blue). … Ciliary motility is essential for the straightening of the body …
The Role of Cilia Motility in Axial Morphogenesis
Z Irons - 2024 - search.proquest.com
… of LR patterning defects and otolith placement abnormalities (… to study its requirement
and role in cilia motility across life … and otolith biogenesis in the inner ear. Nature, 457(7226), …
and role in cilia motility across life … and otolith biogenesis in the inner ear. Nature, 457(7226), …
Daw1 regulates the timely onset of cilia motility during development
EA Bearce, ZH Irons, SB Craig, CJ Kuhns… - …, 2022 - journals.biologists.com
… Motility is powered by dynein arm complexes that are … of LR patterning defects and otolith
placement abnormalities (… Overall, we find that Daw1 is not essential for cilia motility per …
placement abnormalities (… Overall, we find that Daw1 is not essential for cilia motility per …
[HTML][HTML] Kcnb1 plays a role in development of the inner ear
J Jedrychowska, EV Gasanov, V Korzh - Developmental Biology, 2021 - Elsevier
… Otoliths’ formation is mediated by two types of cilia: motile cilia and tether cilia. … Our
analysis demonstrated an essential role for Kcnb1 in development of the inner ear, starting from …
analysis demonstrated an essential role for Kcnb1 in development of the inner ear, starting from …
[HTML][HTML] The forkhead transcription factor Foxj1 controls vertebrate olfactory cilia biogenesis and sensory neuron differentiation
… with motile cilia biogenesis, is expressed in OSNs and required … of olfactory cilia, we observed
that ciliary motility genes are … for ciliary motility proteins, such as the axonemal dyneins, is …
that ciliary motility genes are … for ciliary motility proteins, such as the axonemal dyneins, is …
On the unity and diversity of cilia
… , and ciliary beating and sensing are essential for motility, feeding … of how beating emerges
from cooperative dynein activity at the … kinocilia, but correct otolith placement and subsequent …
from cooperative dynein activity at the … kinocilia, but correct otolith placement and subsequent …
[HTML][HTML] Regionalized protein localization domains in the zebrafish hair cell kinocilium
T Erickson, WP Biggers III, K Williams… - Journal of …, 2023 - mdpi.com
… attachment points for inert masses such as otoliths and otoconia [9]. … motile cilia [11], the
hair cell cilium is non-motile, lacking the inner dynein arms and nexin links found in motile cilia …
hair cell cilium is non-motile, lacking the inner dynein arms and nexin links found in motile cilia …
I1/f dynein and the nexin–dynein regulatory complex form two hubs to control dynein activity and ciliary beating
… essential for ciliary motility in other organisms. Knockdown of the DRC4 ortholog trypanin in
trypanosomes showed that DRC4 is required for optimal ciliary motility … in otolith biogenesis, …
trypanosomes showed that DRC4 is required for optimal ciliary motility … in otolith biogenesis, …
ESCRT subunit CHMP4B localizes to primary cilia and is required for the structural integrity of the ciliary membrane
… defects such as curved body axis, hydrocephalus, otolith … is required for the biogenesis
or maintenance of primary cilia … of primary and motile cilia. J Cell Sci. 2010;123:1785-1795. …
or maintenance of primary cilia … of primary and motile cilia. J Cell Sci. 2010;123:1785-1795. …