[HTML][HTML] Gabaergic interneurons in early brain development: conducting and orchestrated by cortical network activity

D Warm, J Schroer, A Sinning - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
… Concomitantly, the progressive specification of different interneuron subtypes endows the
neocortex with distinct local cortical circuits and region-specific modulation of neuronal firing. …

Interneuron origin and molecular diversity in the human fetal brain

Y Yu, Z Zeng, D Xie, R Chen, Y Sha, S Huang… - Nature …, 2021 - nature.com
… dataset of GABAergic interneurons of the human adult M1 was employed (http://celltypes.brain-map.org/rnaseq).
The 23,992 cells that were assigned as GABA interneurons were …

GABA System as the Cause and Effect in Early Development

I Topchiy, J Mohbat, OO Folorunso… - Neuroscience & …, 2024 - Elsevier
… system serves as a guide and framework for the development of other brain systems.
Despite this early start, the maturation of the GABA system also continues well into the early

Cortical distribution of GABAergic interneurons is determined by migration time and brain size

P Fazzari, N Mortimer, O Yabut, D Vogt… - Development, 2020 - journals.biologists.com
… by the migration time and the increasing size of the developing brain. These data suggest
that the embryonic expansion of the cortex contributes to the rostrocaudal distribution of CINs. …

[HTML][HTML] Prenatal alcohol exposure is a leading cause of interneuronopathy in humans

F Marguet, G Friocourt, M Brosolo, F Sauvestre… - Acta Neuropathologica …, 2020 - Springer
… cortical density disturbances of GABAergic interneurons upon prenatal alcohol exposure, …
The first expresses Dlx1/2 transcription factors, and represents 65% of neocortical GABAergic

Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels

G Miyoshi, Y Ueta, Y Yagasaki… - Proceedings of the …, 2024 - National Acad Sciences
GABAergic interneurons within the neocortex play pivotal roles in local inhibition and have
… We conclude that, although FoxG1 expression is required for GABAergic interneurons to …

[HTML][HTML] Origin, development, and synaptogenesis of cortical interneurons

A Llorca, R Deogracias - Frontiers in Neuroscience, 2022 - frontiersin.org
interneurons that constitute local neocortical circuits and summarize the mechanisms
underlying their development … of TrkB specifically in GABAergic interneurons of the cortex and …

[HTML][HTML] Implications of extended inhibitory neuron development

JY Kim, MF Paredes - International journal of molecular sciences, 2021 - mdpi.com
… , we discuss GABAergic interneuron development in the late … We propose the protracted
development of interneurons at … neocortex, which is triggered by extracellular ambient GABA […

Generation of cerebral cortical GABAergic interneurons from pluripotent stem cells

M Fitzgerald, N Sotuyo, DJ Tischfield, SA Anderson - Stem Cells, 2020 - academic.oup.com
GABAergic interneurons from human pluripotent stem cells. In this concise review, we discuss
recent progress in understanding how interneuron … of rodent and human CIns in vitro. In …

The role of GABAergic signalling in neurodevelopmental disorders

X Tang, R Jaenisch, M Sur - Nature Reviews Neuroscience, 2021 - nature.com
… of GABA A Rs in the adult mouse brain 57 . Neural activity also regulates the functional
development of GABAergic interneurons. … GABA reversal potential was detected in the neocortical