[HTML][HTML] Gabaergic interneurons in early brain development: conducting and orchestrated by cortical network activity
D Warm, J Schroer, A Sinning - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
… Concomitantly, the progressive specification of different interneuron subtypes endows the
neocortex with distinct local cortical circuits and region-specific modulation of neuronal firing. …
neocortex with distinct local cortical circuits and region-specific modulation of neuronal firing. …
Interneuron origin and molecular diversity in the human fetal brain
… dataset of GABAergic interneurons of the human adult M1 was employed (http://celltypes.brain-map.org/rnaseq).
The 23,992 cells that were assigned as GABA interneurons were …
The 23,992 cells that were assigned as GABA interneurons were …
GABA System as the Cause and Effect in Early Development
I Topchiy, J Mohbat, OO Folorunso… - Neuroscience & …, 2024 - Elsevier
… system serves as a guide and framework for the development of other brain systems.
Despite this early start, the maturation of the GABA system also continues well into the early …
Despite this early start, the maturation of the GABA system also continues well into the early …
Cortical distribution of GABAergic interneurons is determined by migration time and brain size
… by the migration time and the increasing size of the developing brain. These data suggest
that the embryonic expansion of the cortex contributes to the rostrocaudal distribution of CINs. …
that the embryonic expansion of the cortex contributes to the rostrocaudal distribution of CINs. …
[HTML][HTML] Prenatal alcohol exposure is a leading cause of interneuronopathy in humans
F Marguet, G Friocourt, M Brosolo, F Sauvestre… - Acta Neuropathologica …, 2020 - Springer
… cortical density disturbances of GABAergic interneurons upon prenatal alcohol exposure, …
The first expresses Dlx1/2 transcription factors, and represents 65% of neocortical GABAergic …
The first expresses Dlx1/2 transcription factors, and represents 65% of neocortical GABAergic …
Developmental trajectories of GABAergic cortical interneurons are sequentially modulated by dynamic FoxG1 expression levels
G Miyoshi, Y Ueta, Y Yagasaki… - Proceedings of the …, 2024 - National Acad Sciences
… GABAergic interneurons within the neocortex play pivotal roles in local inhibition and have
… We conclude that, although FoxG1 expression is required for GABAergic interneurons to …
… We conclude that, although FoxG1 expression is required for GABAergic interneurons to …
[HTML][HTML] Origin, development, and synaptogenesis of cortical interneurons
A Llorca, R Deogracias - Frontiers in Neuroscience, 2022 - frontiersin.org
… interneurons that constitute local neocortical circuits and summarize the mechanisms
underlying their development … of TrkB specifically in GABAergic interneurons of the cortex and …
underlying their development … of TrkB specifically in GABAergic interneurons of the cortex and …
[HTML][HTML] Implications of extended inhibitory neuron development
JY Kim, MF Paredes - International journal of molecular sciences, 2021 - mdpi.com
… , we discuss GABAergic interneuron development in the late … We propose the protracted
development of interneurons at … neocortex, which is triggered by extracellular ambient GABA […
development of interneurons at … neocortex, which is triggered by extracellular ambient GABA […
Generation of cerebral cortical GABAergic interneurons from pluripotent stem cells
M Fitzgerald, N Sotuyo, DJ Tischfield, SA Anderson - Stem Cells, 2020 - academic.oup.com
… GABAergic interneurons from human pluripotent stem cells. In this concise review, we discuss
recent progress in understanding how interneuron … of rodent and human CIns in vitro. In …
recent progress in understanding how interneuron … of rodent and human CIns in vitro. In …
The role of GABAergic signalling in neurodevelopmental disorders
… of GABA A Rs in the adult mouse brain 57 . Neural activity also regulates the functional
development of GABAergic interneurons. … GABA reversal potential was detected in the neocortical …
development of GABAergic interneurons. … GABA reversal potential was detected in the neocortical …