… Dynamic reorganization and remodeling of actin stress fibers … the dominance of cellular
contact guidance over strain … hPSC (derived from human embryonic stem cell line HES3) …

… torque and F-actin assembly at the single cell level. In … , it is difficult to stamp a cell-adhesive
agent on the nonfouling PEG … Straight microstripes can induce cell contact guidance [212]; …

… (PSCs, either embryonic stem cells-ESCs or induced PSCs-iPSCs), terminally differentiate
… in the longitudinal direction are supposed to provide contact guidance and regulate the …

… )) with + or À marking direction of change. Boxplots show the … ,34,58 we observed a severe
disruption of newly formed EP … is that we did not address the biochemical mechanisms by …

… We address new developments in traditional two-… varying diameters exhibited disrupted actin
bundle assembly … either parallel or perpendicular to the fibril direction (Figure 2d). Inhibition …

… ) has been conceived to address these gaps. The project will … We are leveraging human
epidemiological data to guide the … were generated from human-induced pluripotent stem cells [7…

… of contact sites ensure tight interfaces with cell membranes … The effect of curvature-triggered
actin polymerization can be … differentiation of human embryonic stem cells towards definitive …

… anchoring affect E-cadherin clustering in progenitor cell doublets… in these cells, we sought
to interfere with F-actin network stability … To determine how disrupting cortical anchoring of the …

… , using pluripotent stem cells, is desirable. We have developed a differentiation method
that in mice yields pituitary organoids (POs) derived from human embryonic stem cells (hESC). …

… was used to test CP was human embryonic stem cell (hESC) model … is associated with F-actin,
which is organized in several … These effects could be induced either by a disruption in the …