Perfluorooctane sulfonate induced toxicity in embryonic stem cell-derived cardiomyocytes via inhibiting autophagy-lysosome pathway

D Liu, NY Liu, LT Chen, Y Shao, XM Shi, DY Zhu - Toxicology in Vitro, 2020 - Elsevier
… The cells were embedded in pure embedding agent and … cardiomyocyte differentiation via
acting on downstream degradation … Above all, our data demonstrated that PFOS disrupted the …

The influence of reduced graphene oxide on stem cells: a perspective in peripheral nerve regeneration

X Yao, Z Yan, X Wang, H Jiang, Y Qian… - Regenerative …, 2021 - academic.oup.com
… several specific stem cells, including embryonic stem cells (… PNI disrupts the mitochondrial
function and renders excessive … of neuronal cells through direct contact with actin dynamics, …

The human fetal and adult stem cell secretome can exert cardioprotective paracrine effects against cardiotoxicity and oxidative stress from cancer treatment

F Villa, S Bruno, A Costa, M Li, M Russo, J Cimino… - Cancers, 2021 - mdpi.com
… In particular, we aimed to address two main aspects: (i) … mediate pro-survival effects when
acting on cells with very limited … of embryonic stem cells (ES) or induced pluripotent stem cells (…

Therapeutic potential of mesenchymal stem cells and their products in lung diseases—intravenous administration versus inhalation

E Fröhlich - Pharmaceutics, 2021 - mdpi.com
… for preferring adult stem cells to embryonic stem cells. Adult … cell-to-cell contact via
programmed death-1 for MSC-T cell … The immune effects are due to MSCs disrupted by shear …

ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain

EB Choi, M Vodnala, M Zerbato, J Wang, JJ Ho… - Science …, 2021 - science.org
… , disruption of ABCF1 compromises stem cell maintenance, … S2F), consistent with ABCF1
acting as a selective coactivator for OCT4 … To address whether its catalytic activity is required for …

Nuclear mechanics within intact cells is regulated by cytoskeletal network and internal nanostructures

J Zhang, F Alisafaei, M Nikolić, XA Nou, H Kim… - Small, 2020 - Wiley Online Library
… testing methods are based on contact and only allow studying … how disruption of cytoskeletal
components (actin filaments … 4A) and stiffens the actin filament network in the direction of σ ij …

Actin cytoskeleton in mesenchymal-to-amoeboid transition of cancer cells

AY Alexandrova, AS Chikina, TM Svitkina - International review of cell and …, 2020 - Elsevier
… by leukocytes and embryonic progenitor cells. Although both … some initially promising
therapeutic agents, such as inhibitors … , and regulation of the actin cytoskeleton by guidance cues. …

Roles of mesenchymal stem cells and exosomes in interstitial cystitis/bladder pain syndrome

C Wen, L Xie, C Hu - … of Cellular and Molecular Medicine, 2022 - Wiley Online Library
… defects, urothelium permeability disruption, inflammation, … Furthermore, embryonic stem
cell-derived MSCs were … contribute to guide the direction of MSC-based treatments in the future. …

Modifying the tumour microenvironment and reverting tumour cells: New strategies for treating malignant tumours

YQ Cheng, SB Wang, JH Liu, L Jin, Y Liu… - Cell …, 2020 - Wiley Online Library
… mesenchymal stem cell (MSC) transfer and embryonic stem cell-… CAFs that overexpress
α-smooth muscle actin (α-SMA) and … In addition, transmembrane communication and cell contact-…

[HTML][HTML] Nanotechnology shaping stem cell therapy: Recent advances, application, challenges, and future outlook

Y Dong, X Wu, X Chen, P Zhou, F Xu… - Biomedicine & …, 2021 - Elsevier
… will boost the distinction of embryonic stem cells. A dose of … developed to address specifically
the adverse effects produced … toxicity mechanism is actin cytoskeleton disruption. Owing to …