Bio-surface coated titanium scaffolds with cancellous bone-like biomimetic structure for enhanced bone tissue regeneration

B Zhang, J Li, L He, H Huang, J Weng - Acta Biomaterialia, 2020 - Elsevier
… to stimulate the proliferation and differentiation of osteoblasts, … Gene expression was
quantitatively analyzed using … After incubation at 37 C for 24 h, the number of viable bacterial …

Nanostructure and biomimetics orchestrate mesenchymal stromal cell differentiation: An in vitro bioactivity study on new coatings for orthopedic applications

M Sartori, G Graziani, E Sassoni, S Pagani… - Materials Science and …, 2021 - Elsevier
… proportional to the number of viable cells, thus representing a viability assay [32]. …
gene expression and protein variation for some key proteins detected in the present study (osteocalcin

The effect of strontium-substituted hydroxyapatite nanofibrous matrix on osteoblast proliferation and differentiation

SW Tsai, YW Hsu, WL Pan, FY Hsu - Membranes, 2021 - mdpi.com
… , proliferation, alkaline phosphatase activity (ALP) and gene … MG63 osteoblast-like cells
exhibited higher ALP and gene expression … The viability of MG63 osteoblast-like cells on various …

Dual-functionalized apatite nanocomposites with enhanced cytocompatibility and osteogenesis for periodontal bone regeneration

ML Xiang, M Zhu, Z Yang, P He, J Wei… - ACS Biomaterials …, 2020 - ACS Publications
… instructive insight into the design of biomimetic apatite nanocomposites, which holds a great
… downstream osteogenic genes such as type I collagen alpha 1 (Col1a1) and osteocalcin (…

Impact of structural features of Sr/Fe co-doped HAp on the osteoblast proliferation and osteogenic differentiation for its application as a bone substitute

I Ullah, W Zhang, L Yang, MW Ullah, OM Atta… - Materials Science and …, 2020 - Elsevier
… of major functional groups of apatite structure together with the … facilitate the cell viability,
proliferation, and differentiation … RUNX2 gene needs to be downregulated in mature osteoblasts

Evidence of modular responsiveness of osteoblast-like cells exposed to hydroxyapatite-containing magnetic nanostructures

S Scialla, B Palazzo, A Sannino, T Verri, F Gervaso… - Biology, 2020 - mdpi.com
… , also hinting a modular biomimicry of the nanocomposites … We previously reported viability
data which hinted a masking effect … expression analysis of the P53 gene (alias TP53, Tumor …

Biomimetic design and fabrication of sericin-hydroxyapatite based membranes with osteogenic activity for periodontal tissue regeneration

P Ming, P Rao, T Wu, J Yang, S Lu, B Yang… - … in Bioengineering and …, 2022 - frontiersin.org
… /Ser-HAP membranes do not affect the viability of hPDLSCs. … the expression of
osteoblast-related genes, including ALP, … were used to investigate the proliferation of cells treated …

Impact of nano-scale trabecula size on osteoblastic behavior and function in a meso-nano hybrid rough biomimetic zirconia model

H Kitajima, K Komatsu, T Matsuura… - Journal of …, 2023 - jstage.jst.go.jp
genes collagen type I alpha 1, osteopontin, and osteocalcin … to establish the biological
viability of this unique surface … UV photofunctionalization promotes nano-biomimetic apatite

Biomimetic fabrication of icariin loaded nano hydroxyapatite reinforced bioactive porous scaffolds for bone regeneration

Y Hu, S Cao, J Chen, Y Zhao, F He, Q Li, L Zou… - Chemical Engineering …, 2020 - Elsevier
… ’ mineralization, and a thin apatite layer was covered on the … Cell viability showed osteoblasts
cultured with different … gene expression, and further promote the differentiation of the …

Design strategies and biomimetic approaches for calcium phosphate scaffolds in bone tissue regeneration

F Pupilli, A Ruffini, M Dapporto, M Tavoni, A Tampieri… - Biomimetics, 2022 - mdpi.com
osteocalcin is found to be attached to the collagen structure and … effects on cement injectability,
making CPCs a viable … by the outstanding upregulation of genes involved in both early (…