[HTML][HTML] Mechanisms for the development of heart failure and improvement of cardiac function by angiotensin-converting enzyme inhibitors

SK Bhullar, AK Shah, NS Dhalla - Scripta Medica, 2022 - scindeks.ceon.rs
… Increases in heart rate, as well as alterations in myocardial extracellular matrix … captopril
has been shown to reduce cardiovascular responses to acute stress in the post-infarction heart

Acute poisoning by chlorpyrifos differentially impacts survival and cardiorespiratory function in normotensive and hypertensive rats

AV Aitken, VS Minassa, TJ Batista… - Chemico-Biological …, 2024 - Elsevier
… We investigated for possible underlying mechanisms … ) and heart rate (ΔHR) (bottom panel)
after Bezold-Jarisch reflex (… acute poisoning can be prevented by captopril, an ACE inhibitor …

Pharmacological anti-remodelling effects of disease-modifying drugs in heart failure with reduced ejection fraction

M Correale, P Mazzeo, L Tricarico, F Croella… - Clinical Drug …, 2022 - Springer
mechanism is represented by the reduction in sympathetic activity, through the reduction in
renal afferent nervous activity and the suppression of central reflex mechanisms. … or captopril

… receptors and superoxide anion production in hypothalamic paraventricular nucleus contribute to capsaicin-induced excitatory renal reflex and sympathetic activation

Y Qiu, F Zheng, C Ye, AD Chen, JJ Wang, Q Chen… - Neuroscience …, 2020 - Springer
… signaling mechanism in the PVN that mediates the ERR. … The blood pressure, heart rate,
and renal sympathetic nerve … enzyme inhibitor captopril had no significant effects on these …

The renin-angiotensin system and cardiovascular autonomic control in aging

AJ Miller, AC Arnold - Peptides, 2022 - Elsevier
… , increases cardiovascular sympathetic outflow and impairs the … reflex control of heart rate
in aged animal models. The precise mechanisms underlying the deleterious cardiovascular

Autonomic Dysreflexia in Spinal Cord Injury: Mechanisms and Prospective Therapeutic Targets

CT Trueblood, A Singh, MA Cusimano… - The …, 2023 - journals.sagepub.com
… It is often seen with symptoms such as unstable heart rate, reduced … This leads to an abnormal
reflexive response to unpleasant … such as captopril and cilazapril. These two drugs, which …

Hypotensive effects of melatonin in rats: Focus on the model, measurement, application, and main mechanisms

D Cvikova, H Sutovska, K Babarikova… - Hypertension Research, 2022 - nature.com
… autonomic and reflex regulation of cardiovascular activity [81]. … -converting enzyme inhibitor
(captopril) reduced blood pressure … heart rate but not the blood pressure rhythm [103]. Similar …

[HTML][HTML] Autonomic nervous system and cardiac neuro-signaling pathway modulation in cardiovascular disorders and Alzheimer's disease

A Elia, S Fossati - Frontiers in Physiology, 2023 - frontiersin.org
effects. Since other peptidases may produce AT- II, this mechanism might explain the failure
of captopril … improvement of vagal reflexes, stabilization of the heart rhythm and control of the …

[HTML][HTML] Emerging topics on basic research in hypertension: interorgan communication and the need for interresearcher collaboration

K Shinohara - Hypertension Research, 2023 - nature.com
mechanism known as the adipose afferent reflex [9, 10]. … evidence that captopril has the
potential to rebalance the … gut flora by captopril may contribute to the hypotensive effect of …

[HTML][HTML] Drug-induced chronic cough and the possible mechanism of action

H Ding, C Shi, X Xu, L Yu - Annals of Palliative Medicine, 2020 - apm.amegroups.org
… for the dry cough associated with ACEI captopril therapy (35). … , IP3 inhibitor) blocks the
captopril-induced augmentation of … effect on the receptors involved in the cough reflex remains …