Effects of long-term metformin and lifestyle interventions on cardiovascular events in the diabetes prevention program and its outcome study

RB Goldberg, TJ Orchard, JP Crandall, EJ Boyko… - Circulation, 2022 - Am Heart Assoc
… The effect of metformin and intensive lifestyle intervention on the metabolic syndrome:
the Diabetes Prevention Program randomized trial.Ann Intern Med. 2005; 142:611–619. …

Safety and effectiveness of metformin plus lifestyle intervention compared with lifestyle intervention alone in preventing progression to diabetes in a Chinese …

L Zhang, Y Zhang, X Wang, L Dong, Q Li… - The Lancet Diabetes & …, 2023 - thelancet.com
… that metformin combined with lifestyle intervention was more … to diabetes compared with
lifestyle intervention alone. In … , with the metformin plus lifestyle intervention group showing extra …

Association of intensive lifestyle and metformin interventions with frailty in the diabetes prevention program outcomes study

HP Hazuda, Q Pan, H Florez… - The Journals of …, 2021 - academic.oup.com
… Findings from the present study suggest that lifestyle intervention combining achievement
and maintenance of weight loss and increased moderate-intensity physical activity when …

Effect of metformin and lifestyle interventions on mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study

CG Lee, B Heckman-Stoddard, D Dabelea… - Diabetes …, 2021 - Am Diabetes Assoc
… cardiovascular disease mortality (23,24), and because metformin and lifestyle interventions
… (4), we hypothesized that metformin and lifestyle modification may also lower the risk for all-…

Effects of lifestyle modification in polycystic ovary syndrome compared to metformin only or metformin addition: A systematic review and meta-analysis

CH Kim, SJ Chon, SH Lee - Scientific reports, 2020 - nature.com
… Additionally, metformin is used in the treatment of PCOS but its role remains unclear. We
compared the effects of lifestyle modification (LSM) + metformin and metformin alone on PCOS. …

Long-term effects of lifestyle and metformin interventions in DPP on bone density

AV Schwartz, Q Pan, VR Aroda, JP Crandall… - Osteoporosis …, 2021 - Springer
… The lifestyle intervention group in Look AHEAD also … Our findings provide reassurance that
intensive lifestyle intervention … of an intensive lifestyle intervention or metformin for diabetes …

Short and long term effect of treatment non-pharmacological and lifestyle in patients with metabolic syndrome

AD Brandão, JH da Silva… - … & Metabolic Syndrome, 2020 - Springer
effect of the comprehensive cardiac rehabilitation program and intensive lifestyle intervention
in metabolic syndrome … assignment to intensive lifestyle intervention, metformin therapy, or …

Weight loss, lifestyle intervention, and metformin affect longitudinal relationship of insulin secretion and sensitivity

E Vazquez Arreola, WC Knowler… - … & Metabolism, 2022 - academic.oup.com
… We investigated effects of weight loss, an intensive lifestyle intervention (ILS), and metformin
on the relationship between insulin secretion and sensitivity using repository data from …

A randomized controlled trial of metformin in women with components of metabolic syndrome: intervention feasibility and effects on adiposity and breast density

E Tapia, DE Villa-Guillen, P Chalasani… - Breast cancer research …, 2021 - Springer
… trial of metformin in overweight/… metabolic syndrome to assess the potential of metformin
for primary breast cancer prevention. This manuscript reports intervention feasibility and effects

Effect of intensive lifestyle intervention on bodyweight and glycaemia in early type 2 diabetes (DIADEM-I): an open-label, parallel-group, randomised controlled trial

S Taheri, H Zaghloul, O Chagoury… - The lancet Diabetes & …, 2020 - thelancet.com
… assess whether an intensive lifestyle intervention would lead … , compared the effects of an
intensive lifestyle intervention with … (1:1) either to the intensive lifestyle intervention group or the …