… specifically developed to improve the pharmacokinetic and safety profile of … activity against
many IMP-nonsusceptible Gram-negative bacteria (10). IMP-C/REL has antimicrobial activity …

… pharmacokinetic/pharmacodynamic value (pK/pD) for different dosages of ceftolozane/tazobactam
in … In the case of tazobactam, since there is no intrinsic antimicrobial activity, different …

… and pharmacokinetic factors of presently available antimicrobial agents … Piperacillin
tazobactam, a time-dependent antibiotic, is a … of time-dependent antibacterial activity compared …

… suggests that tazobactam (TAZ) target exposures to restore piperacillin bacteriostatic and
1 log 10 bactericidal activity against Enterobacterales are fT> the piperacillin/tazobactam (TZP) …

… The PK/PD data for tazobactam were also considered in reviewing the PTZ breakpoints. …
appreciable bactericidal advantage with the addition of tazobactam compared with piperacillin …

… between piperacillin/tazobactam and warfarin have been written in each package insert,
there have been few reports on whether PIPC/TAZ affects the anticoagulation effect of warfarin …

… impact of optimal joint pharmacokinetic/pharmacodynamic (PK/PD) target attainment of
continuous infusion (CI) piperacillin–tazobactam … CI piperacillin–tazobactam monotherapy …

… interplay between piperacillin and tazobactam pharmacokinetics, particularly in patients with
ARC. The lessons from previous studies underscore the complexity of antibiotic dosing and …

… In recent years, piperacillin-tazobactam has been prescribed … broad-spectrum antimicrobial
activity against the pathogens … , the pharmacokinetics data of piperacillin/tazobactam is …

… changes that affect antibiotic pharmacokinetics. Piperacillin/tazobactam administered by …
Available data suggest that maximum bactericidal activity occurs when the dose is maintained …