… vs. continuous moderate-intensity aerobic exercise for improving neurotransmitter level and neurocognitive performance in individuals with Parkinson's disease

CL Tsai, TK Lin - Mental Health and Physical Activity, 2023 - Elsevier
… The target-onset time windows for calculating the mean N2 and P3 amplitudes were between
… The pathology of PD is marked by a neurotransmitter (eg, dopamine) deficiency. In animal …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
… therapeutic effect of dopaminergic treatments gradually diminishes with time. Exercise training,
… multiple neurotransmitter system disorders, cellular dysfunction and neuroinflammation. …

BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
… enhances the survival of dopaminergic neurons, improves dopaminergic neurotransmission
and motor performance. Pharmacological therapies of PD are symptom-targeting, and their …

Clinical applications of exercise in Parkinson's disease: what we need to know?

S Machado, D Teixeira, D Monteiro… - Expert Review of …, 2022 - Taylor & Francis
… survival of dopaminergic striatal neurons in patients with Parkinsons [… targeted at outcomes
related to individual disease … well as specific groups of neurotransmitters that are of particular …

Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson's disease

…, A Patel, D Matuskey, ED Morris, S Tinaz - … Parkinson's Disease, 2024 - nature.com
Parkinsons disease (PD) is a neurodegenerative disorder characterized by the loss of
dopaminergic neurons … and maintained their HR within the targeted range (Supplementary Fig. 1). …

… exercise with different intensities on cerebral dopamine/norepinephine/serotonin metabolites and executive-related oculomotor control in individuals with Parkinson's …

CL Tsai, CY Pan, TC Wang, YT Tseng… - … and Physical Activity, 2024 - Elsevier
target in the prosaccade condition, or to look away from the … of neurotransmitter metabolites
and any exercise-induced … , although neither exercise mode had any significant effect on …

NADPH and mitochondrial quality control as targets for a circadian-based fasting and exercise therapy for the treatment of Parkinson's disease

WM Curtis, WA Seeds, MP Mattson, PC Bradshaw - Cells, 2022 - mdpi.com
… phospholipids, deficits in neurotransmitter production, and compromised cellular signaling
pathways. Therefore, MQC is a target for PD treatment that is upstream of dopamine and α-…

Vulnerabilities of aging and biological effects of physical activity provide new clues for interventions in Parkinson's disease

NI Bohnen - The Journals of Gerontology: Series A, 2020 - academic.oup.com
… of striatal dopaminergic losses (estimated 30% attenuation of this relationship). Therefore,
nigrostriatal dopaminergic neurotransmission could serve as a potential intervention target to …

Treatment options for motor and non-motor symptoms of Parkinson's disease

FC Church - Biomolecules, 2021 - mdpi.com
neurotransmitters, dopamine delivers messages throughout the central nervous system (CNS)
[54]. Dopamine … They found 145 registered and ongoing clinical trials targeting PD spread …

The role of exercise in Parkinson's Disease

MA Almikhlafi - Neurosciences Journal, 2023 - nsj.org.sa
… control neurotransmitters. However, pharmacological treatment with dopaminergic agonists
used in the management of PD symptoms was found to worsen the symptoms of sleeping …