Impact of anti-citrullinated protein antibodies on progressive systemic bone mineral density loss in patients with early rheumatoid arthritis after two years of treat-to …

S Bugatti, L Bogliolo, A Manzo, L De Stefano… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid factor (RF) and ACPA were centrally determined … The impact of ACPA beyond
inflammation found here is in … demonstrating progression of bone erosions despite absent or …

Predictors of new bone erosion in rheumatoid arthritis patients receiving conventional synthetic disease-modifying antirheumatic drugs: analysis of data from the …

T Takeuchi, S Soen, N Ishiguro… - Modern …, 2021 - academic.oup.com
bone erosion was observed in 90 patients (29.4%). Univariate analysis identified female sex,
anti-cyclic citrullinated peptide (CCP) antibody positivity, rheumatoid factorbone erosion. In …

Current view on the pathogenic role of anti-citrullinated protein antibodies in rheumatoid arthritis

A Catrina, A Krishnamurthy, B Rethi - RMD open, 2021 - rmdopen.bmj.com
antibodies reactive with the Fc-part of IgG (rheumatoid factor (… as pain and bone erosion,
and potentially facilitate arthritis … of antibodies to citrullinated fibrinogen peptides (in this case …

Rheumatoid arthritis in the view of osteoimmunology

M Auréal, I Machuca-Gayet, F Coury - Biomolecules, 2020 - mdpi.com
… and bone is responsible for the articular bone erosions. The … between inherited genetic
factors and environmental triggers … , including anti-citrullinated peptide antibodies (ACPAs), are …

Antibodies to citrullinated proteins (ACPA) associate with markers of osteoclast activation and bone destruction in the bone marrow of patients with rheumatoid arthritis

W Kurowska, I Slowinska, Z Krogulec… - Journal of Clinical …, 2021 - mdpi.com
… Studies in mice suggest that anti-citrullinated protein antibodies (ACPAs) can trigger …
activation and bone erosion in RA bone marrow. Anti-cyclic citrullinated peptide antibodies (anti-…

Anti-citrullinated protein antibodies in patients with rheumatoid arthritis: biological effects and mechanisms of immunopathogenesis

CY Wu, HY Yang, JH Lai - International Journal of Molecular Sciences, 2020 - mdpi.com
… , including rheumatoid factor (RF) and anti-citrullinated peptide antibodies (ACPAs), are …
FcγR and increase its capacity to induce osteoclast activation and bone erosion [154]. This …

Effect of antiresorptive and bone forming treatments in bone erosions in rheumatoid arthritis

AB Azuaga-Piñango, P Peris - Medicina Clínica (English Edition), 2020 - Elsevier
… of this disease, such as anti-citrullinated peptide antibodies (ACPA), present from preclinical
… sedimentation rate (ESR) and presence of rheumatoid factor (RF) and ACPA. Again, all …

Anti-cyclic citrullinated peptide antibodies are associated with radiographic damage but not disease activity in early rheumatoid arthritis diagnosed in 2006–2011

M Ziegelasch, A Boman, K Martinsson… - Scandinavian Journal …, 2020 - Taylor & Francis
… Objective: The discovery of anti-citrullinated protein antibodies (… IgM-class rheumatoid
factor (RF), ESR (mm/h), and C-… The number of erosions calculated for the cohorts with X-rays …

Rheumatoid arthritis and osteoimmunology: The adverse impact of a deregulated immune system on bone metabolism

D Andreev, K Kachler, G Schett, A Bozec - Bone, 2022 - Elsevier
bone erosion. The results derived from these surveys can help to further optimize …
autoantibodies, namely rheumatoid factors (RFs) and anti-citrullinated protein antibodies (ACPAs). …

Anti-citrullinated protein antibodies as biomarkers in rheumatoid arthritis

NH Trier, G Houen - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
… combination with rheumatoid arthritis; cyclic citrullinated peptide, CCP, anti-CCP, … and that
some ACPAs even protect against arthritis and bone erosions [… ACPAs and rheumatoid factors