Diabetic cardiomyopathy: From mechanism to management in a nutshell

S Khan, SS Ahmad, MA Kamal - Endocrine, Metabolic & …, 2021 - ingentaconnect.com
… stream components like insulin receptor substrate (IRS-1) and … β-islet cells considerably
mitigates alloxan-induced hyper… -1-mediated vasoconstriction in severe chronic heart failure. …

THE MOLECULAR BASIS OF DIABETIC CARDIOMYOPATH

ASM Ali Sultan - 2022 - scholarworks.uaeu.ac.ae
… to further investigate how diabetes and diabesity affects the … used to assess the effects of
diabetes and diabesity on ion … and structures associated with cardiac muscle contraction. Heart …

The contribution of cardiac fatty acid oxidation to diabetic cardiomyopathy severity

QG Karwi, Q Sun, GD Lopaschuk - Cells, 2021 - mdpi.com
… function following acute ischemia in alloxan-induced diabetic dog … is a more oxygen-efficient
substrate compared to fatty acids in the heart. … , which is an energy-starved heart [196]. …

Ameliorating impact of coenzyme Q10 on the profile of adipokines, cardiomyopathy, and hematological markers correlated with the glucotoxicity sequelae in diabetic …

YJ Jbrael, BK Hamad - Plos one, 2024 - journals.plos.org
… with acute hyperglycemia in STZ-induced diabetic rats. … On the last day of the three-week
treatment period, animals were starved … TMB is a substrate for horseradish peroxidase (HRP), a …

Guidelines on models of diabetic heart disease

LC Heather, AD Hafstad, GV Halade… - American Journal …, 2022 - journals.physiology.org
… a shift in cardiac energy substrate utilization from carbohydrate to … thought to be energy-starved
and characterized by reduced … STZ and alloxan can also be used to induce T1D in the …

Effect of Ethanolic Extract of Parquetina nigrescens (Bullock) Leaves on Some Indices of Myocardial Infarction in Isoproterenol Administered Rats

AA Qudus - 2021 - search.proquest.com
… and risk of MI in alloxan-induced diabetes was reported. … skin rashes) and polyphagia (increased
hunger). The period of … substrates, significantly inhibits or delays the oxidation of those …

[PDF][PDF] … STUDIES ON AQUEOUS EXTRACT AND NANOPARTICLES OF MORINGA OLEIFERA STEM BARK ON ALLOXAN INDUCED–DIABETES (TYPE I) IN MALE …

RA ALIYU - 2023 - portal.bazeuniversity.edu.ng
… in Alloxan – induced diabetic in male Wistar rat…………………………65 Figure 2: Effect of
… Therefore, the emphasis of this investigation was on how Alloxan-induced Type I diabetes

Chronic inflammatory status observed in patients with type 2 diabetes induces modulation of cytochrome P450 expression and activity

L Darakjian, M Deodhar, J Turgeon… - International journal of …, 2021 - mdpi.com
… In alloxan-induced diabetic rats, induction of cyp1a2 resulted in … In alloxan diabetic rats,
it was also shown that T2DM … rises in drug plasma levels of substrates of these enzymes (drugs …

YAP1 induces hyperglycemic stress-mediated cardiac hypertrophy and fibrosis in an AKT-FOXM1 dependent signaling pathway

A Mondal, S Das, J Samanta, S Chakraborty - Archives of Biochemistry …, 2022 - Elsevier
… The animals were starved overnight prior to injection. The control … effect of hyperglycemia
on cardiomyocyte, mice under experiment were injected with alloxan to mimic type II diabetic

Kynurenine pathway in diabetes mellitus—novel pharmacological target?

K Kozieł, EM Urbanska - Cells, 2023 - mdpi.com
… depending on the extent of the substrate saturation of AMSD. Then… Additionally, childhood
severe acute malnutrition has been … in the model of DM induced by alloxan in rabbits [109]. Trp …