… , where the clearance of reactive oxygen species was impaired [163,164]. The second … -43
in ALS [165]. The third indication includes altered RNA metabolism in non-coding RNAs such …

… in ALS pathogenesis. As nuclear FUS plays a crucial role in modulating RNA metabolism, …
Moreover, we have recently reported an altered metabolic profile in induced astrocytes from …

… amyotrophic lateral sclerosis (ALS), the most frequent motoneuron (MN) disorder in adults.
Notably, defective RNA metabolism … splicing of mRNAs was altered in FUS-related ALS, with …

… activate downstream pathways, often altering RNA metabolism. Mutations and changes in …
mutation linked to ALS alters the splicing function of TDP-43, resulting in changed RNAs and …

… pathways of AD, PD, and ALS. Our results pointed out a different degree of RNA metabolism
and dysregulation involvement in AD, PD, and ALS, highlighting a different role for lncRNAs …

… /or a gain of toxic function of these ALS-linked RBPs play a … interaction, causing aberrant
RNA metabolism, and by disturbing … and RNA splicing, abnormal RNA transport, altered mRNA …

… evidence has improved our understanding of the pathomechanisms that lead to amyotrophic
lateral sclerosis (ALS) and … Impaired RNA metabolism, enhanced aggregation of protein-…

… the roles of altered RNA metabolism and RNA-mediated toxicity … , and C9ORF72 that cause
amyotrophic lateral sclerosis (ALS) and … have on RNA metabolism, as well as how RNA itself …

… of RNA metabolism has emerged as key player in multiple neurological disorders 1 . Amyotrophic
lateral sclerosis (ALS… For MeRIP–RT–qPCR, the m 6 A-modified GLuc RNA (NEB) was …

… the hypothesis that RNA dysregulation could be a key contributor to familiar ALS pathogenesis.
… the involvement of an altered RNA metabolism in sporadic ALS cases. Studies based on …