… However, due to the broad range of cellular functions of the FOXO family members … been
described as the “FOXO code” [48]. In conclusion, sequence, and structural variability among …

… the reasons for the existence, in a given genome, of gene families that encode for very similar
proteins. The FOXO … In this review, I will discuss the functional implications of the existence …

… Several reviews have summarized the role of PTMs in the regulation of FOXO, and we
refer to these for more detail 16,17 (Supplementary Box 2 and Supplementary Tables). …

… The purpose of this review article is to briefly summarize the metabolic roles played by the …
Thus, the balance between PI3K-mTORC2-AKT and Foxo1 signaling in metabolically relevant …

… To determine the role of FOXO shuttling dynamics in the … reporters to measure the temporal
dynamics of FOXO1 and FOXO3 in … These stresses were chosen due to the different FOXO–…

… whether variations in the structures and dynamics of the FOXO FH domains … the structural
variability within the FOXO family we examined in more detail the region between H4 and the N-…

… Consistently, various mutations in the FOXO DBD increase the level of p-FOXO by Akt kinase
[74], hinting at weakened DNA binding and subsequent nuclear-cytoplasmic translocation. …

… of the levels of the APC/CCDH1 inhibitor EMI1/FBXO5 through Forkhead box O (FOXO)-…
We find that ATR-dependent FOXO activation acts as a timer to restrict the window in which …

… ChREBP and/or FOXO1 depending on the cell type studied, we examined the … To further
characterize the contribution of FoxO1 to the regulation of Txnip in … Data and code availability …

… In vitro binding assays indicated that Rotund physically binds to 23 FoxO to form the
FoxO combinatorial code. These findings broaden our 24 understanding of the complexity of …