Acute respiratory distress syndrome: potential of therapeutic interventions effective in treating progression from COVID-19 to treat progression from other illnesses—a …

EJ Ragel, LK Harris… - BMJ Open Respiratory …, 2023 - bmjopenrespres.bmj.com
… Although surfactants do not improve mortality or MV duration … to COVID-19-induced ALI/ARDS
patients. The incidence of … as a promising focus of future research for ARDS as well as …

[HTML][HTML] Progress in preclinical studies of macrophage autophagy in the regulation of ALI/ARDS

C Liu, K Xiao, L Xie - Frontiers in Immunology, 2022 - frontiersin.org
At present, there is no specific treatment for ALI/ARDS. The … of dead alveolar cells and excess
alveolar surfactant (66, 67). In … potential therapeutic approach for ARDS patients, and future

Complement as a vital nexus of the pathobiological connectome for acute respiratory distress syndrome: an emerging therapeutic target

Z Yang, SE Nicholson, TS Cancio, LC Cancio… - Frontiers in …, 2023 - frontiersin.org
… for ALI/ARDS via its … /therapeutic potential and future direction of ALI/ARDS care with the
ultimate goal of better defining mechanistic subtypes (endotypes and theratypes) through new …

Extracellular vesicles in the pathogenesis and treatment of acute lung injury

Q Hu, S Zhang, Y Yang, JQ Yao, WF Tang… - Military Medical …, 2022 - Springer
… AEC-IIs also secrete alveolar surfactants, regulate surfactant … to ALI/ARDS progression, as
it can decrease surfactant production … EVs and neutrophils during ALI/ARDS progression. This …

[HTML][HTML] Trends in research on acute lung injury/acute respiratory distress syndrome associated with viral pneumonia from 1992 to 2022: a 31-year bibliometric …

L Zhang, S Mei, B Zhu, Z Zhao - Frontiers in Medicine, 2023 - frontiersin.org
… The treatment and management of ALI/ARDS may be … using Citespace to serve as a reference
for relevant future research. … such as alveolar surfactant supplement therapy and moderate …

Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines

W Zhu, Y Zhang, Y Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
Surfactant is mainly composed of lipids and related proteins, … drug that can effectively treat
ALI/ARDS. In light of this, … be done on immunotherapy for ALI in the future. It is important to fully …

Stem cell derived exosomes-based therapy for acute lung injury and acute respiratory distress syndrome: a novel therapeutic strategy

B Xu, S Chen, M Liu, C Gan, J Li, G Guo - Life Sciences, 2020 - Elsevier
… derived exosomes related to ALI/ARDS and provide insights … A series of therapeutic
strategies including surfactants [8], … Liquid therapy may lead to renal injury at different levels and …

Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury

GP Fadanni, JB Calixto - Cytokine & Growth Factor Reviews, 2023 - Elsevier
… Therefore, through a comprehensive analysis of the … treatment strategy that could be a
selective alternative to global IL-6 inhibition in the future, but its therapeutic potential in ALI/ARDS

Secretory Phospholipase A2 Enzymes in Acute Lung Injury

E Letsiou, YM Htwe, SM Dudek - Cell Biochemistry and Biophysics, 2021 - Springer
… The ALI/ARDS spectrum of severe inflammatory conditions is … in the field and potential areas
of research for future studies. … or pulmonary surfactant, or indirectly through the generation of …

… patterns involving TLR and NLR synergisms in COVID-19, ALI/ARDS and sepsis cytokine storms: a review and model making novel predictions and therapeutic …

R Root-Bernstein - International journal of molecular sciences, 2021 - mdpi.com
… recognizes heat shock and surfactant proteins and high mobility … -associated ALI/ARDS
requires viral activation, while TLR4 … of ignorance that needs to be rectified by future research. …