VIP: A COVID-19 Therapeutic that Blocks Coronavirus Replication

J Javitt, JG Youssef - Available at SSRN 3670129, 2020 - papers.ssrn.com
… VIP promises to be effective against future viral threats and may have broad applicability …
on Surfactant Production: A pathologic hallmark of the ALI/ARDS is the damage to the surfactant

[HTML][HTML] Acute lung injury caused by sepsis: how does it happen?

B Sun, M Lei, J Zhang, H Kang, H Liu… - Frontiers in Medicine, 2023 - ncbi.nlm.nih.gov
surfactant into the plasma, leading to it is expression at a low level in alveolar lavage fluid
(119). Pulmonary surfactant … effective therapeutic drugs and methods will emerge in the future, …

[HTML][HTML] A systematic review of biomarkers multivariately associated with acute respiratory distress syndrome development and mortality

P Van Der Zee, W Rietdijk, P Somhorst, H Endeman… - Critical Care, 2020 - Springer
… This study provides a synopsis of ARDS biomarkers that could be used for future research …
development in the at-risk population. Similar results were seen for surfactant protein D (SpD) …

Pulmonary Contusions and ARDS

E Gamberini, L Bissoni, G Scognamiglio… - … for the Acute Care …, 2021 - Springer
… This work has also clearly demonstrated that while … represent promising targets for future
therapies. Unfortunately, evidence-… use for the prevention and treatment of ALI/ARDS [69, 70]. …

[HTML][HTML] Lower oligomeric form of surfactant protein D in murine acute lung injury induces M1 subtype macrophages through calreticulin/p38 MAPK signaling pathway

D Li, L Pan, X Zhang, Z Jiang - Frontiers in Immunology, 2021 - frontiersin.org
… However, serum SP-D is significantly increased in ALI/ARDS … for the diagnosis and evaluation
of ALI/ARDS (1–3). SP-D has … promising therapeutic strategy in the treatment of ALI/ARDS. …

The exogenous surfactant pre-treatment attenuates ventilator-induced lung injury in adult rats

RN Chirico, NA de Matos, T de Freitas Castro… - Respiratory Physiology …, 2022 - Elsevier
at end-expiration. Therefore, this study aimed to analyze the effects of intranasal surfactant
treatment on … This research work supports the future performance of studies that assess the …

[HTML][HTML] ARDS after Pneumonectomy: How to Prevent It? Development of a Nomogram to Predict the Risk of ARDS after Pneumonectomy for Lung Cancer

A Mazzella, S Mohamed, P Maisonneuve, A Borri… - Cancers, 2022 - mdpi.com
… who underwent pneumonectomy during the period 2014–2021. … to a depletion of glutathione
surfactant production and to an … 24 h can favor the risk of ALI/ARDS in the 72 h after surgery. …

[HTML][HTML] Future trends in nebulized therapies for pulmonary disease

SD McCarthy, HE González, BD Higgins - Journal of Personalized …, 2020 - mdpi.com
… personalized therapeutic approach to ALI/ARDS whereby specific therapeutic candidates …
premature pediatric patients but while aerosolized surfactant was well tolerated at the doses …

[HTML][HTML] Molecular hydrogen is a potential protective agent in the management of acute lung injury

Y Zhang, J Zhang, Z Fu - Molecular Medicine, 2022 - Springer
… treat ALI/ARDS is imperative; these may also be useful in the … to further the treatment of ALI
and COVID-19 in the future. … immune cells and secrete surfactant proteins on their apical side. …

Investigation of the global outcomes of acute respiratory distress syndrome with the effect of COVID-19 in publications: a bibliometric analysis between 1980 and 2020

M ZENGİN, R BALDEMİR - Kırıkkale Üniversitesi Tıp Fakültesi …, 2021 - dergipark.org.tr
… constitutes an important health problem during the COVID-19 … was used in order to estimate
the number of future studies. … on the treatment of ARDS and the topic of ALI/ARDS. Wang et …