[HTML][HTML] Droplet microarrays for cell culture: effect of surface properties and nanoliter culture volume on global transcriptomic landscape

S Chakraborty, V Gourain, M Benz, JM Scheiger… - Materials Today Bio, 2021 - Elsevier
… Our results have shown that HeLa-CCL2 cells cultured on DMAs fabricated with various …
volumes on cell culture, we analyzed the transcriptomic landscape of cells cultured on DMA. …

[HTML][HTML] Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections

M Chen, M Tachedjian, GA Marsh, J Cui… - Frontiers in …, 2020 - frontiersin.org
… In summary, we used RNA-seq to compare bat and human cell lines infected with HeV or
CedV. We found that CedV caused a stronger innate immune response than did HeV. It is …

[HTML][HTML] LncRNA TP53TG1 plays an anti-oncogenic role in cervical cancer by synthetically regulating transcriptome profile in HeLa cells

Y Cheng, N Huang, Q Yin, C Cheng, D Chen… - Frontiers in …, 2022 - frontiersin.org
HeLa cell line, coupled with RNA-seq sequences, to comprehensively reveal the biological
functions of TP53TG1 in HeLa cell … TP53TG1-OE model in HeLa cell line to explore its role in …

Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns

M Salvadores, F Fuster-Tormo, F Supek - Science Advances, 2020 - science.org
cell lines identified as originating from the skin often exhibited a UV mutational signature. We
cataloged 366 “golden set” cell lines in which transcriptomic … of origin in cell line panels can …

[HTML][HTML] Epigenetic and transcriptomic regulation landscape in HPV+ cancers: biological and clinical implications

R Castro-Oropeza, P Piña-Sánchez - Frontiers in Genetics, 2022 - frontiersin.org
… Interestingly, transcriptomic analysis has revealed that although a vast majority of the human
genome is transcribed into RNAs, only 2% of transcripts are translated into proteins. The …

Deciphering the Genetic Orchestra: Unveiling Splice Form Dynamics in Human Cell Lines

VA Arzumanian, OI Kiseleva, EV Poverennaya - 2024 - preprints.org
… 4 cell lines and the prevalence of Q9H2G2-1 in one cell line. Non-canonical variant Q9H2G2-2,
according to the results of analysis of data from the TCGA project, was low expressed in …

[HTML][HTML] Profiling the non-genetic origins of cancer drug resistance with a single-cell functional genomics approach using predictive cell dynamics

M Meyer, A Paquet, MJ Arguel, L Peyre… - Cell systems, 2020 - cell.com
… to its own genome-wide transcriptomic profile. As a proof of principle, … HeLa cells to
demonstrate that cell dynamics can discriminate the transient transcriptional states at the origin of …

[HTML][HTML] An integrated landscape of protein expression in human cancer

AF Jarnuczak, H Najgebauer, M Barzine, DJ Kundu… - Scientific data, 2021 - nature.com
… Interestingly, when examining correlations within specific lineages (ie tumours of one
type to all cell line types) we found that cell lines from a corresponding lineage were not …

[HTML][HTML] Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

TLH Okholm, S Sathe, SS Park, AB Kamstrup… - Genome medicine, 2020 - Springer
… In bladder cancer cell lines, we show that circCDYL interacts with IGF2BP1 and IGF2BP2
and that depletion of circCDYL or these RBPs disturb several hallmarks of cancer. Specifically, …

… in transcriptional and posttranscriptional regulation of cancer-associated genes by modulating their expression and alternative splicing profiles in HeLa cells

Y Song, BA, F Wang, MA, Y Wei, MA… - … in Cancer Research …, 2021 - journals.sagepub.com
… Although HeLa cells are widely used in tumor and molecular biology studies, our … cell lines.
While an in-depth exploration on how ATP5A1 promotes cellular apoptosis in HeLa cells was …