Neuroprotection through G-CSF: recent advances and future viewpoints

V Rahi, S Jamwal, P Kumar - Pharmacological Reports, 2021 - Springer
… , G-CSF reduces the glutamate-induced neuronal cell death and … G-CSF is a hematopoietic
growth factor which mobilize … In compilation, the G-CSF is the potent neural ligand and …

Hematopoietic stem cell mobilization

HH Chang, YS Liou, DS Sun - Tzu Chi Medical Journal, 2022 - journals.lww.com
… The interaction between Notch2 and its ligand also maintains HSC … G-CSF activates the
sympathetic neurons innervating BM by … FGF-23 can counteract the function of CXCR4 and then …

Role of Granulocyte-Colony Stimulating Factor (G-CSF) in Immune Regulation and Neuroprotection

J Dumbuya, H Prentice, JY Wu - Journal of Cellular …, 2023 - scientificarchives.com
… the numbers of hematopoietic stem/progenitor cells in patients … of G-CSF in neuronal protection
since it protects neurons … found additional up-regulated ligand-receptor pairs enriched in …

New insight into the mechanism of granulocyte colony-stimulating factor (G-CSF) that induces the mobilization of neutrophils

A Theyab, M Algahtani, KF Alsharif, YM Hawsawi… - …, 2021 - Taylor & Francis
… The ability of G-CSF to mobilize hematopoietic stem cells … of G-CSF exerts neuroprotective
effects on damaged neurons … Each ligand of G-CSF interacts with the CRH domain of one G-…

Colony stimulating factors in the nervous system

V Chitu, F Biundo, ER Stanley - Seminars in immunology, 2021 - Elsevier
… regulators of hematopoiesis, colony-stimulating factors (CSFs) … This review summarizes the
cellular sources, patterns of … ) and granulocyte (G-CSF) colony stimulating factors within the …

G-CSF in tumors: Aggressiveness, tumor microenvironment and immune cell regulation

I Karagiannidis, E Salataj, ESA Egal, EJ Beswick - Cytokine, 2021 - Elsevier
… is also expressed in other tissues such as the placenta, adult neural stem cells, B-cells and
hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death

Direct potential modulation of neurogenic differentiation markers by granulocyte-colony stimulating factor (G-CSF) in the rodent brain

J Kozole, R Heydn, E Wirkert, S Küspert, L Aigner… - Pharmaceutics, 2022 - mdpi.com
… of a single high dose of the hematopoietic growth factor G-CSF [1] upon neurogenic and non-…
(A–I) show results for markers of neuronal differentiation from early neurogenesis to mature …

G-CSF reduces loss of dopaminergic neurons by inhibiting TNF-α and IL-1β in mouse model of Parkinson's disease

DD Zhang, CY Zhang, YX Zhang, HP Cui… - International Journal …, 2023 - Taylor & Francis
factor (G-CSF) is a hematopoietic growth factor existing in neutrophils, glial cells and
neurons… Our results showed that G-CSF significantly increased the TH-ip cells in the SNpc and …

The contribution of stem cell factor and granulocyte colony-stimulating factor in reducing neurodegeneration and promoting neurostructure network reorganization …

J He, T Russell, X Qiu, F Hao, M Kyle, L Chin, LR Zhao - Brain Research, 2020 - Elsevier
… (G-CSF) are involved in neuroprotection and neuronal … This study aims to determine the
efficacy of SCF + G-CSF on post-… (G-CSF) are the key hematopoietic growth factors to regulate …

Long-term beneficial effects of hematopoietic growth factors on brain repair in the chronic phase of severe traumatic brain injury

X Qiu, S Ping, M Kyle, L Chin, LR Zhao - Experimental Neurology, 2020 - Elsevier
hematopoietic growth factors, stem cell factor (SCF) and granulocyte colony–stimulating factor
(G-CSF… than SCF and G-CSF alone treatments in enhancing GAP-43 neural expression in …