… hypoxia-related genes. We got 30 highly expressed hypoxia-related genes in pancreatic
cancer … data and clinical information for pancreatic cancer were downloaded from UCSC (https://…

… to investigate the role of hypoxia in PSCs and pancreatic cancer cells, and examine the
potential protective effect of curcumin against hypoxia-induced pancreatic cancer progression. It …

… We next examined the effects of HIF1A depletion on tumor … how HIF1A modulates intratumoral
hypoxia and stroma during … 9 (a surrogate marker of tumor hypoxia) and stromal contents …

… factors as well as directly regulate the hypoxic response pathways. In this review, we will
focus on hypoxia-mediated epigenetic alterations and their impact on pancreatic cancer. …

… Pancreatic cancer (PC) remains one of the most … metastasis, with a 1-year overall survival
rate of approximately 20%. The hypoxic microenvironment, induced by intratumoral hypoxia, …

… with pancreatic cancer. In this review, we discuss the molecular mechanisms underlying
hypoxia-induced aggressive and therapeutically resistant phenotypes in both pancreatic …

… be altered by hypoxic conditions in PDAC cells 25 , the effect of hypoxia on HA metabolism
is unknown. In the present study, we investigated the relationship between hypoxia and HA …

… that HIF3α promotes invasion and metastasis by transcriptionally … of hypoxia and its effect
on several cellular pathways, we will discuss the role of hypoxia on metastasis (invasion and …

… In an extremely nutrient-deficient and hypoxic environment resulting from … cancer metabolism.
In addition, we also discuss the unclear role of OXPHOS in pancreatic cancer metastasis. …

… hypoxia-driven PSC activation and inhibit pancreatic cancer cell EMT and invasion, and …
suppresses the activation of hypoxia-enhanced HIF-1α and abolishes hypoxia-induced SDF…