[HTML][HTML] Impact of tumor localization and molecular subtypes on the prognostic and predictive significance of p53 expression in gastric cancer

B Grosser, M Kohlruss, J Slotta-Huspenina… - Cancers, 2020 - mdpi.com
Patients with MSI-H and aberrant p53 showed the worst survival … impact of p53 in GC differs
according to tumor localization and CTx. Altered p53 is characteristic for MSI-L, and the p53

[HTML][HTML] Prognosis and genomic landscape of liver metastasis in patients with breast cancer

C Tian, S Liu, Y Wang, X Song - Frontiers in Oncology, 2021 - frontiersin.org
… the prognosis of patients with BCLM and focused on prognosis prediction for these …
Interestingly, ESR1 and TP53 were the most mutually exclusive mutant gene pair in LMs (pairwise …

[PDF][PDF] Role of p53 as a prognostic marker in breast carcinoma and its correlation with tumor size, tumor grade and lymph node metastasis

B Jindal, A Mohan, V Ansari… - Indian Journal of …, 2020 - pdfs.semanticscholar.org
… So, aim of this study is to find out role of p53 overexpression in breast carcinoma and its …
impact of p53 in predicting clinical outcome of breast cancer patients with visceral metastasis

p53 and BLC2 immunohistochemical expression across molecular subtypes in 1099 early breast cancer patients with long-term follow-up: an observational study

A Fabi, M Mottolese, A Di Benedetto, F Sperati… - Clinical Breast …, 2020 - Elsevier
… in improvements in the ability to predict a patient’s risk of BC … clinicians in tailoring
treatment decisions for patients at the individual level. Nevertheless, despite the positive results

[HTML][HTML] Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients

A Muendlein, K Geiger, S Gaenger, T Dechow… - Scientific Reports, 2021 - nature.com
… effective tool to predict the course of metastatic breast cancer (MBC… ctDNA to evaluate the
impact of cancer driven mutations on the … showing that breast cancer patients with TP53 mutant …

[HTML][HTML] Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a …

C Callens, K Driouch, A Boulai, Z Tariq, A Comte… - Genome Medicine, 2021 - Springer
treatment for advanced disease. We describe here the molecular landscape of metastatic
breast cancer … Private mutations in metastasis in more than two patients were detected in TP53, …

TP53 mutations and outcomes in breast cancer: reading beyond the headlines

A Shahbandi, HD Nguyen, JG Jackson - Trends in cancer, 2020 - cell.com
… These include using imprecise methods to determine tumor TP53 status and using different
clinical endpoints to assess predictive or prognostic significance of TP53 mutations. Perhaps …

Mutant p53 on the path to metastasis

Q Tang, Z Su, W Gu, AK Rustgi - Trends in cancer, 2020 - cell.com
… of function mutant p53 promotes cancer cell motility, invasion, and metastasis. … p53 that
foster metastasis in different types of cancers. We also discuss the prognostic value of mutant p53

[HTML][HTML] … p53 immunohistochemical expression is associated with poor prognostic parameters and disease-free survival in triple-negative metaplastic breast carcinoma

AA Hashmi, A Sajid, M Hussain, S Zia, S Islam… - Cureus, 2021 - ncbi.nlm.nih.gov
… Concordant with our findings, they also found a significant association of p53 expression with
p53 positivity was predictive of outcome in breast cancer patients with visceral metastasis […

[HTML][HTML] Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer

A Bortolini Silveira, FC Bidard, ML Tanguy, E Girard… - … Breast Cancer, 2021 - nature.com
… to evaluate whether they have a prognostic impact on patients’ survival. This analysis …
patients (TP53, PIK3CA, GATA3, ESR1, KMT2C, and CDH1). We observed that patients with TP53