[HTML][HTML] Impact of tumor localization and molecular subtypes on the prognostic and predictive significance of p53 expression in gastric cancer
B Grosser, M Kohlruss, J Slotta-Huspenina… - Cancers, 2020 - mdpi.com
… Patients with MSI-H and aberrant p53 showed the worst survival … impact of p53 in GC differs
according to tumor localization and CTx. Altered p53 is characteristic for MSI-L, and the p53 …
according to tumor localization and CTx. Altered p53 is characteristic for MSI-L, and the p53 …
[HTML][HTML] Prognosis and genomic landscape of liver metastasis in patients with breast cancer
C Tian, S Liu, Y Wang, X Song - Frontiers in Oncology, 2021 - frontiersin.org
… the prognosis of patients with BCLM and focused on prognosis prediction for these …
Interestingly, ESR1 and TP53 were the most mutually exclusive mutant gene pair in LMs (pairwise …
Interestingly, ESR1 and TP53 were the most mutually exclusive mutant gene pair in LMs (pairwise …
[PDF][PDF] Role of p53 as a prognostic marker in breast carcinoma and its correlation with tumor size, tumor grade and lymph node metastasis
B Jindal, A Mohan, V Ansari… - Indian Journal of …, 2020 - pdfs.semanticscholar.org
… So, aim of this study is to find out role of p53 overexpression in breast carcinoma and its …
impact of p53 in predicting clinical outcome of breast cancer patients with visceral metastasis…
impact of p53 in predicting clinical outcome of breast cancer patients with visceral metastasis…
p53 and BLC2 immunohistochemical expression across molecular subtypes in 1099 early breast cancer patients with long-term follow-up: an observational study
A Fabi, M Mottolese, A Di Benedetto, F Sperati… - Clinical Breast …, 2020 - Elsevier
… in improvements in the ability to predict a patient’s risk of BC … clinicians in tailoring
treatment decisions for patients at the individual level. Nevertheless, despite the positive results …
treatment decisions for patients at the individual level. Nevertheless, despite the positive results …
[HTML][HTML] Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients
A Muendlein, K Geiger, S Gaenger, T Dechow… - Scientific Reports, 2021 - nature.com
… effective tool to predict the course of metastatic breast cancer (MBC… ctDNA to evaluate the
impact of cancer driven mutations on the … showing that breast cancer patients with TP53 mutant …
impact of cancer driven mutations on the … showing that breast cancer patients with TP53 mutant …
[HTML][HTML] Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a …
C Callens, K Driouch, A Boulai, Z Tariq, A Comte… - Genome Medicine, 2021 - Springer
… treatment for advanced disease. We describe here the molecular landscape of metastatic
breast cancer … Private mutations in metastasis in more than two patients were detected in TP53, …
breast cancer … Private mutations in metastasis in more than two patients were detected in TP53, …
TP53 mutations and outcomes in breast cancer: reading beyond the headlines
… These include using imprecise methods to determine tumor TP53 status and using different
clinical endpoints to assess predictive or prognostic significance of TP53 mutations. Perhaps …
clinical endpoints to assess predictive or prognostic significance of TP53 mutations. Perhaps …
Mutant p53 on the path to metastasis
… of function mutant p53 promotes cancer cell motility, invasion, and metastasis. … p53 that
foster metastasis in different types of cancers. We also discuss the prognostic value of mutant p53 …
foster metastasis in different types of cancers. We also discuss the prognostic value of mutant p53 …
[HTML][HTML] … p53 immunohistochemical expression is associated with poor prognostic parameters and disease-free survival in triple-negative metaplastic breast carcinoma
… Concordant with our findings, they also found a significant association of p53 expression with
… p53 positivity was predictive of outcome in breast cancer patients with visceral metastasis […
… p53 positivity was predictive of outcome in breast cancer patients with visceral metastasis […
[HTML][HTML] Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer
A Bortolini Silveira, FC Bidard, ML Tanguy, E Girard… - … Breast Cancer, 2021 - nature.com
… to evaluate whether they have a prognostic impact on patients’ survival. This analysis …
patients (TP53, PIK3CA, GATA3, ESR1, KMT2C, and CDH1). We observed that patients with TP53 …
patients (TP53, PIK3CA, GATA3, ESR1, KMT2C, and CDH1). We observed that patients with TP53 …