… — oxidation of phospholipids in the environment following tissue injury. We discuss how
oxidized phospholipids (… By contrast, PAMP detection in the presence of oxidized products may …

… profoundly impact the activity of innate immune phagocytes. … responsible for detecting bacterial
products in immune cells. NOD1/… -PC oxidation and controls transcriptional responses via …

… cellular effects in the context of acute innate immune response. The seminal study by Bochkov
… It appears that phospholipid oxidation products modulate the immune response to induce …

… oxidation of certain substrates in the presence of H 2 O 2 to generate potent reactive and
oxidant products … Peroxide simply diffuses through phospholipid bilayers of the cell membranes. …

… robust peroxidation of three classes of phospholipids during … amounts of phospholipid
peroxidation products were found in … have differential effects on the innate immune system. …

… Innate immune responses are primarily mediated by pathogen … One indicator of tissue
damage is the release and oxidation of … form), translate protein products for encapsulation of that …

… Many fatty acid peroxidation products, for example, 4-… Reactive electrophilic species generated
by fatty acid peroxidation … of bilayer barrier function as a consequence of PL oxidation has …

… Upon tissue injury and cell death, membrane phospholipids … through oxidation of membrane
component phospholipids … indicate that different oxidation products may have differential …

… Lipid peroxidation products such as oxidized phospholipids are associated with
inflammation and … Innate immune detection of lipid oxidation as a threat assessment strategy. …

… Oxidized phospholipids (OxPLs), complex mixtures of phospholipid oxidation products
generated during normal … Oxidation of these phospholipids generates a large variety of oxidized …