… lipid metabolism, APOE has a key role in controlling … The Apoe deficient mice, Apoe
hypomorphic mice and APOE knock-in mice have been key resources in the field of atherosclerosis …

… We established the apolipoprotein E-deficient atherosclerosis … -1 expression in atherosclerosis
mice after baicalin treatment. … activated in atherosclerosis and played essential role in the …

… atherosclerosis without lowering hypercholesterolemia. It is important to elucidate these
functions … ApoE is an important apolipoprotein that plays a central role in lipoprotein metabolism. …

… In conclusion, our findings suggest that butyrate plays a multi-faceted role in its athero-protective
effect, at least an important part of which is mediated by modulation of lipid metabolism, …

… main cause of atherosclerosis, ASCVD remains the main … main pathophysiological mechanisms
through which Lp(a) may contribute to atherogenesis and evidence supporting its role in …

… , an essential role in the pathogenesis of atherosclerosis has … As a main cellular component
in the ruptured atherosclerotic … play a critical role in the progression of atherosclerosis. The …

… In addition to ApoE4 playing a role in Aβ generation, ApoE4 and Aβ can also have a
significant role in the ApoE-inflammatory cascade. As previously mentioned, ApoE4 has a role in …

… Inflammation has a vital role in the development and progression of atherosclerosis, and
thus it contributes to increased risk of cardiovascular events [43]. Inflammation promotes …

… metabolism, apoC1 plays a key role in the regulation of HDL remodelling [5,6,7,8,9,10,11].
This wide range of effects together with a possible role in the modulation of inflammation …

… to be involved in the pathogenesis of atherosclerosis. As such, macrophages play a central
role in the initiation and progression of atherosclerosis. Macrophages are diverse in their …