Increased APOE glycosylation plays a key role in the atherogenicity of L5 low‐density lipoprotein

LY Ke, HC Chan, CC Chen, CF Chang… - The FASEB …, 2020 - Wiley Online Library
Apolipoprotein E (APOE) content is increased in L5, but what role APOE plays in L5 function
… and activity within the atherosclerotic plaque,9,10 an important area of study has been to …

Natural products: The role and mechanism in low‐density lipoprotein oxidation and atherosclerosis

S Zhang, L Li, W Chen, S Xu, X Feng… - Phytotherapy …, 2021 - Wiley Online Library
pivotal role of low-density lipoprotein (LDL) oxidation in the initiation and progression of
atherosclerosis. … pro-atherogenic and biomarker role of oxidized LDL in atherosclerosis. We also …

[HTML][HTML] Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice

X Jiao, Y Yang, L Li, H Yu, Y Yang, J Li, Y Du, J Zhang… - Atherosclerosis, 2020 - Elsevier
… identifies a prominent role for ANGPTL8 in the development of atherosclerotic lesions and
provides a mechanism explaining the link between ANGPTL8 and atherosclerosis, which is …

The role of oxidative stress in atherosclerosis

M Batty, MR Bennett, E Yu - Cells, 2022 - mdpi.com
… in both apolipoprotein E deficient (ApoE −/− ) mice and in ApoE −/… proteins have a critical
role in atherosclerosis through their … A protective role of UCP2 in atherosclerosis has also been …

Recognition of oxidized lipids by macrophages and its role in atherosclerosis development

NV Mushenkova, EE Bezsonov, VA Orekhova… - Biomedicines, 2021 - mdpi.com
… in apolipoprotein E deficient mice [16]. Since then, it has become clear that atherosclerosis
is … Macrophage response to oxLDL species plays an important role in atherosclerotic lesion …

Glycoursodeoxycholic acid ameliorates atherosclerosis and alters gut microbiota in apolipoprotein e–deficient mice

K Huang, C Liu, M Peng, Q Su, R Liu… - Journal of the …, 2021 - Am Heart Assoc
… hypothesis, the potential role and associated mechanism of GUDCA in atherosclerosis were
… cell formation plays a crucial role in the progression of atherosclerosis, we first explored the …

VLDL (very-low-density lipoprotein)-Apo E (apolipoprotein E) may influence Lp (a)(lipoprotein [a]) synthesis or assembly

…, B Cariou, M Krempf, E Nobécourt-Dupuy - Arteriosclerosis …, 2020 - Am Heart Assoc
key role of the LDLR in Lp(a) catabolism 13 to a key role of PCSK9 in Lp(a) production. In
humans, Lp(a) fractional catabolic rates (FCR) were found to be similar in patients with FH and …

Enhanced Atherosclerosis in Apolipoprotein E Knockout Rabbits: Role of ApoB48-Rich Remnant Lipoproteins

J Fan, Y Chen, M Niimi, H Zhao, X Tang… - Frontiers in … - frontiersin.org
… Introduction: Apolipoprotein E (apoE) acts as a binding molecule for both the low-… is essential
for facilitating the hepatocyte uptake of lipoproteins containing apoB. The absence of apoE

The resolvin D2–GPR18 axis is expressed in human coronary atherosclerosis and transduces atheroprotection in apolipoprotein E deficient mice

M Bardin, SC Pawelzik, J Lagrange, A Mahdi… - Biochemical …, 2022 - Elsevier
… in relation to the presence of atherosclerotic lesions and its cellular components. … in
atherosclerotic compared with healthy human coronary arteries. Furthermore, apolipoprotein E (ApoE

Tissue factor in atherosclerosis and atherothrombosis

SP Grover, N Mackman - Atherosclerosis, 2020 - Elsevier
Apolipoprotein E (APOE) gene (Apoe −/− ) fed a normal diet or a high fat and high cholesterol
western type diet develop atherosclerotic … , which play a critical role in monocyte activation …