… In the past few decades, the crucial role of APOE in the pathogenesis of atherosclerosis has
been recognized [14, 15]. More recently, several studies have investigated the relationships …

… metabolism and atherosclerosis in Apoe − / − mice. We identified an important role of
endothelial miR-21-DDAH1-ADMA-eNOS-NO signalling in DMY-ameliorated atherosclerotic lesion …

… of peptides derived from apolipoprotein AI (apoA-I) and apolipoprotein E (apoE) [10,11],
although other apolipoprotein mimetic peptides, such as apolipoprotein C-II (apoC-II) [12] or …

… Despite its demonstrated contribution to atherosclerotic cardiovascular disease burden, we
… address key knowledge gaps and future directions required to mitigate the atherosclerotic …

… Replacement of apoAI with apoAII in the KI rabbits resulted in several prominent changes in
… rich in apoE along with apoAIV and apoAV, which are known to play important roles in the …

… , the role of TREML4 in the pathogenesis of cardiovascular disease remains incompletely
defined. Since macrophages play a key role in … a possible role in atherosclerosis. Analysis of …

… vivo using an established apolipoprotein E-knockout (ApoE −/- ) … of the cytokine in the
atherosclerosis lesions. IL10 delivered … Systemic and chronic inflammation plays critical roles in …

… atherosclerosis and further uncovered the underlying mechanism. Given the important role
of … , we postulated that TFA may inhibit atherosclerosis through regulating miR-33 expression …

… Hence, mtROS plays an important role in the pathophysiology of atherosclerosis by … whether
idebenone can protect against atherosclerosis in apolipoprotein E-deficient (apoE−/−) mice. …

… the search terms (“APOE” OR “apolipoprotein e”) AND (“meta-analysis” OR “pooled analysis”).
The review was restricted to meta-analyses of APOE allele health outcome associations …