Mechanistic insights into the oxidized low‐density lipoprotein‐induced atherosclerosis
… a prominent role in the onset of notorious atherosclerosis, a disease of medium to large
arteries. Atherosclerosis … lipoproteins (HDLs), endogenous apolipoprotein E (ApoE), and ApoA-I …
arteries. Atherosclerosis … lipoproteins (HDLs), endogenous apolipoprotein E (ApoE), and ApoA-I …
ApoE (Apolipoprotein E) in brain pericytes regulates endothelial function in an isoform-dependent manner by modulating basement membrane components
Y Yamazaki, M Shinohara, A Yamazaki… - Arteriosclerosis …, 2020 - Am Heart Assoc
… of apoE (apolipoprotein E) encoded by the APOE gene is to transport cholesterol and other
lipids in the brain, apoE … Our results collectively support a critical role of brain pericytes in …
lipids in the brain, apoE … Our results collectively support a critical role of brain pericytes in …
[HTML][HTML] Apolipoprotein E deficiency induces a progressive increase in tissue iron contents with age in mice
J Ma, C Qian, Y Bao, MY Liu, HM Ma, MQ Shen, W Li… - Redox biology, 2021 - Elsevier
… apolipoprotein E (ApoE) with development of Alzheimer disease (AD) and atherosclerosis
led us to hypothesize that ApoE … To confirm the essential role of ApoE in iron homeostasis, we …
led us to hypothesize that ApoE … To confirm the essential role of ApoE in iron homeostasis, we …
Oxidative stress and antioxidants in atherosclerosis development and treatment
AV Poznyak, AV Grechko, VA Orekhova… - Biology, 2020 - mdpi.com
… Oxidative stress plays an important role in atherosclerotic … Apolipoprotein E knock-out (apoE
-/- ) mice that are also … are characterized by accelerated atherosclerosis development in the …
-/- ) mice that are also … are characterized by accelerated atherosclerosis development in the …
[HTML][HTML] … stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis
… that HDAC-dependent pathways play an important role in mediating Nox up-regulation, …
Together, the data of present study extend to experimental atherosclerosis the role of HDAC …
Together, the data of present study extend to experimental atherosclerosis the role of HDAC …
Implications for the role of lipopolysaccharide in the development of atherosclerosis
AM Gorabi, N Kiaie, A Khosrojerdi… - Trends in cardiovascular …, 2022 - Elsevier
… events during atherosclerosis development. In this review article, we attempt to clarify the
role of LPS in the initiation and progression of atherosclerotic lesion development. …
role of LPS in the initiation and progression of atherosclerotic lesion development. …
The role of macrophages in the pathogenesis of atherosclerosis
AV Blagov, AM Markin, AI Bogatyreva, TV Tolstik… - Cells, 2023 - mdpi.com
… one of the leading roles in the development of the pathological process in atherosclerosis, in
… that participated in the pathogenesis of atherosclerosis are distinguished, and the effect that …
… that participated in the pathogenesis of atherosclerosis are distinguished, and the effect that …
Expanding biology of PCSK9: roles in atherosclerosis and beyond
… These powerful treatments reduce the incidence of atherosclerosis by at least 20%. Since
2008, novel targets of PCSK9 began to be defined, thereby expanding its roles beyond LDLc …
2008, novel targets of PCSK9 began to be defined, thereby expanding its roles beyond LDLc …
Corylin inhibits vascular cell inflammation, proliferation and migration and reduces atherosclerosis in ApoE-deficient mice
CC Chen, HY Li, YL Leu, YJ Chen, CJ Wang, SH Wang - Antioxidants, 2020 - mdpi.com
… critical in preventing the development of atherosclerosis. … and VSMCs play important roles
in atherosclerosis progression, the … the atherosclerotic plaque in the apolipoprotein E (ApoE)-…
in atherosclerosis progression, the … the atherosclerotic plaque in the apolipoprotein E (ApoE)-…
An update on the role of PCSK9 in atherosclerosis
E Yurtseven, D Ural, K Baysal… - Journal of atherosclerosis …, 2020 - jstage.jst.go.jp
… of PCSK9, particularly its direct effects on atherosclerotic … plays a significant role in every step
of atherosclerotic plaque … 1 (MCP1) in the atherosclerotic aortas of Apo E KO mice43). MCP-…
of atherosclerotic plaque … 1 (MCP1) in the atherosclerotic aortas of Apo E KO mice43). MCP-…