… conditions, targeting autophagy is a promising target in atherosclerosis treatment [7]. … target
for the treatment of atherosclerosis. Degradation of lipid by autophagy plays a vital role in the …

… apolipoprotein E-deficient (Apoe −/− ) or low-density lipoprotein receptor–deficient (LDLR −/−
) mice reduces atherosclerosis … been found in human atherosclerotic plaques 13 ; however, …

… , they play an important role in triggering atherosclerosis through active lipid accumulation
… atherosclerotic plaques. Proatherogenic modified low-density lipoprotein (mLDL) is the main …

… Chronic inflammation in aortic tissue is a crucial driver of the formation of atherosclerotic …
CD68 play an important role in the formation and development of atherosclerotic plaques and …

… Therefore, we postulate that reduced or defective synthesis, plays a critical role in SPM:LT
imbalances in atherosclerosis. There are several possible mechanisms that may underly this …

… This review summarizes the effect of EVs in atherosclerosis development, progression and
… ambivalent roles in senescence and hemostasis. This review will also highlight the role of …

… , apolipoprotein E knockout (ApoE –/– ) mice, genetically modified mice frequently utilized as
the animal study model for initiating atherosclerosis… -1α played a crucial role in this process. …

… is the APOE gene coding for the apolipoprotein E protein (apoE)… This review will focus
on the critical role of apoE in AD … receptors may also increase the risk of atherosclerosis, …

… These powerful treatments reduce the incidence of atherosclerosis by at least 20%. Since
2008, novel targets of PCSK9 began to be defined, thereby expanding its roles beyond LDLc …

… the structure, function, and metabolism of TRL, and their pathophysiological role in atherosclerotic
cardiovascular disease (ASCVD). Key points are (i) a working definition of normo- and …