Binding characteristics of thyroid hormone distributor proteins to thyroid hormone metabolites

RMS Jongejan, ME Meima, WE Visser, TIM Korevaar… - Thyroid, 2022 - liebertpub.com
… are excreted as thyroacetic acid (TA0) in urine (4), although others found only … Competitive
protein binding assay … Third, our LC-MS/MS method measures only total THM concentrations …

Linking Transthyretin-Binding Chemicals and Free Thyroid Hormones: In Vitro to In Vivo Extrapolation Based on a Competitive Binding Model

K Huang, W Zhou, J Fu, Q Zhang, Y Teng… - Environmental …, 2023 - ACS Publications
method based on a competitive binding model to quantify the effect of TTR-binding chemicals
on free thyroid hormones … with the calculated or measured results from other studies (TBG: …

Thyroid stimulating hormone and thyroid hormones (triiodothyronine and thyroxine): an American Thyroid Association-commissioned review of current clinical and …

K Van Uytfanghe, J Ehrenkranz, D Halsall, K Hoff… - Thyroid, 2023 - liebertpub.com
… T3 is predominantly protein bound (99.7%) and a direct measurement of fT3 is theoretically
… Optimization of a method to detect levothyroxine and related compounds in serum and urine

Mass spectrometry in the diagnosis of thyroid disease and in the study of thyroid hormone metabolism

M Borsò, P Agretti, R Zucchi… - Mass Spectrometry …, 2022 - Wiley Online Library
… reliable techniques for routine measurements, despite large variations in serum-binding protein
… Briefly, the method made use of 100 μl of plasma or urine, which were added with stable …

Molecular interactions of thyroxine binding globulin and thyroid hormone receptor with estrogenic compounds 4-nonylphenol, 4-tert-octylphenol and bisphenol A …

IA Sheikh - Life sciences, 2020 - Elsevier
binding pocket of protein is taken into consideration while performing the IFD experiment.
The procedure … TSH levels and higher BPA concentration in urine [44]. In subjects working in …

The free hormone hypothesis: when, why, and how to measure the free hormone levels to assess vitamin D, thyroid, sex hormone, and cortisol status

DD Bikle - Journal of Bone and Mineral Research Plus, 2021 - academic.oup.com
Methods to measure free hormone levels are problematic as the free … thyroid hormone (measured
as protein bound iodine) was quite low in these patients along with increased urinary

[HTML][HTML] Binding of common organic UV-filters to the thyroid hormone transport protein transthyretin using in vitro and in silico studies: Potential implications in health.

EY Cotrina, Â Oliveira, J Llop, J Quintana… - Environmental …, 2023 - Elsevier
Protein bound 125 IT 4 and free 125 IT 4 were separated by … method, which uses radiolabeled
T 4 in the competitive … and fetal samples and in paired urine and blood samples. It has …

Characterization of molecular interactions between cannabidiol and human plasma proteins (serum albumin and γ-globulin) by surface plasmon resonance …

C Liu, A Cai, H Li, N Deng, BP Cho, NP Seeram… - … of Pharmaceutical and …, 2022 - Elsevier
… CBD’s plasma protein binding characteristics and shed light on … We evaluated the binding
capacity of thyroxine using the … various competition binding techniques to explore the binding

Endocrine disruption: Molecular interactions of environmental bisphenol contaminants with thyroid hormone receptor and thyroxine-binding globulin

MA Beg, IA Sheikh - Toxicology and Industrial Health, 2020 - journals.sagepub.com
… In addition, using IFD technique, the best docking poses for native ligands T4 and T3 with …
In pregnant women, urinary BPS was associated with an increase in serum levels of free T4 …

[HTML][HTML] Hormone immunoassay interference: a 2021 update

K Ghazal, S Brabant, D Prie… - Annals of laboratory …, 2022 - synapse.koreamed.org
… of binding proteins, and free thyroid hormone estimates in … Measuring an analyte using
another method is very useful and … is not found in urine; thus, discordant results with urine, for …