Metabolome wide association study of serum DDT and DDE in pregnancy and early postpartum

X Hu, S Li, P Cirillo, N Krigbaum, VL Tran… - Reproductive …, 2020 - Elsevier
… that maternal p,p’-DDT, o,p’-DDT and p,p’-DDE exposure were associated with differential
metabolic … Consistent with these human studies, direct exposure of rat tissue to p,p’-DDE

Metabolic signatures of the exposome—quantifying the impact of exposure to environmental chemicals on human health

M Orešič, A McGlinchey, CE Wheelock, T Hyötyläinen - Metabolites, 2020 - mdpi.com
… of p,p′-DDE and hexachlorobenzene (HCB) levels were linked to a set of lipid-related
metabolites involved in key metabolic … between the levels of DDE, β-HCH, HCB, PCBs and lipids, …

Biomarkers of metabolic disorders and neurobehavioral diseases in a PCB-exposed population: what we learned and the implications for future research

JJ Simhadri, CA Loffredo, T Trnovec, LP Murinova… - Environmental …, 2020 - Elsevier
… on metabolic and neurological dysfunction/disease of a PCB-exposed human population. …
, providing a clue that this “gene fingerprinting” approach could indeed lead us to identify …

[HTML][HTML] Environmental chemical burden in metabolic tissues and systemic biological pathways in adolescent bariatric surgery patients: A pilot untargeted …

D Valvi, DI Walker, T Inge, SM Bartell, T Jenkins… - Environment …, 2020 - Elsevier
… mechanisms underlying environmental toxicity in humans. … clusters associated with p,p’-DDE,
HCB and PBDE-47 in … metabolic pathways where unique to the POP exposure and …

Fingerprint of Persistent Organic Pollutants (POPs) in the Environment: Ecological Assessment and Human Health Effects

F Beduk, S Aydin, A Ulvi, ME Aydin - Water and Wastewater Management …, 2022 - Springer
… (PCBs) and hexachlorobenzene (HCB) from the group of … People are exposed to POPs
by consuming contaminated … and disrupt biosynthesis or metabolism of steroid hormones […

Organochlorines and Polycyclic Aromatic Hydrocarbons as fingerprint of exposure pathways from marine sediments to biota

A Traina, A Ausili, M Bonsignore, D Fattorini… - Marine pollution …, 2021 - Elsevier
… In this work, we present an unprecedented dataset of Hg, HCB, PCBs and priority PAHs …
, HCB and Hg in sediments and biota were elaborated to evaluate the fingerprint association …

Metabolomics: a new approach in the evaluation of effects in human beings and wildlife associated with environmental exposition to POPs

M Acosta-Tlapalamatl, C Romo-Gómez… - Toxics, 2022 - mdpi.com
… associated with environmental exposure to POPs in wildlife and human populations and …
such as p,p′-DDE, and HCB are associated with variation in lipid metabolism, including fatty …

Investigation of dichlorodiphenyltrichloroethane (DDT) on xenobiotic enzyme disruption and metabolomic bile acid biosynthesis in DDT-sprayed areas using wild rats

K Motohira, YB Yohannes, Y Ikenaka… - Journal of Veterinary …, 2023 - jstage.jst.go.jp
… Our results suggest that DDT exposure affects gene expression in wild rats living in DDT-…
The metabolic fingerprint of p,p′-DDE and HCB exposure in humans. Environ Int 88: 60–66…

[HTML][HTML] NMR-based metabolomic analysis of human plasma to examine the effect of exposure to persistent organic pollutants

SY Jang, Y Jung, DH Lee, GS Hwang - Chemosphere, 2022 - Elsevier
metabolic changes and effects of PCBs and OCPs exposure … in a large number of human
samples and investigated the … : p,p'-DDT; p,p'-DDE; β-hexachlorocyclohexane (HCH); HCB; …

Metabolic pathway analysis in HepG2 cells exposed to organoclorines using null diffusion-based enrichment

JA Lopera-Rodríguez, M Zuluaga… - 2021 IEEE 2nd …, 2021 - ieeexplore.ieee.org
… to elucidate the metabolic pathways involved in organochlorines exposure using … Human
chronic exposure is widely studied because it can cause serious diseases, and acute exposure