… For the present rat pharmacokinetic data, non-compartmental analysis was conducted
using WinNonlin® Ver. 3.1 software (NCA200 and 201; Certara, Inc., Princeton, NJ, USA). This …

… good prediction performance. A fully mechanistic model of enterohepatic recirculation warrants
… Non-compartmental analysis (NCA) was performed for the simulated concentration-time …

… contact between the membrane and recirculating media (Fig. … Additionally, the recirculating
medium can be accessed with a … access to the cell compartment during seeding, longitudinal …

… is typically based on a threecompartment pharmacokinetic (… in silico study of the performance
of a model-based controller of … To test the controller performance, we physically close the …

… physiologically based pharmacokinetic modeling (PBPK) Now in its second edition,
Physiologically Based Pharmacokinetic (… for the physiologically based pharmacokinetic modeling …

… based on a priori known organ physiology, as opposed to empirical temporal and spatial
kinetic characteristics, forms the basis of physiologically based pharmacokinetic … recirculation-…

… compartment in a physiologically based pharmacokinetic (… In short, each tissue compartment
is divided into a vascular-, … flow (\(Q\)) and recirculate to the venous blood supply using the …

… into the advanced compartmental absorption and transit (ACAT) … this study, we employed a
physiologically-based pharmacokinetic/… factors on the in vivo performance of warfarin tablets. …

… To capture the kinetics and inter-organ recirculation of endogenous and exogenously
administered T cells, we developed a physiologically-based compartmental model of T cell …

… tumor compartment (not utilized in the present study). The 17th “other” compartment comprises
all … All tissues are connected by anatomical plasma/blood flow and lymphatic recirculation …