… The pathological convergence of tau and amyloid β-peptide (… of the cerebral cortices of
3XTg-AD mice occurred well … , VDAC has been found on the plasma membrane (plVDAC) of cells. …

… Ca 2+ in cortical neurons of 3xTg-AD animals was 247 nmol/… concentration transients near
the plasma membrane, both in … , two brain functions that are largely impaired in AD, by CaM. …

… impairment. However, melatonin treatment attenuated … regions including the cerebral cortex
and hippocampus which … that Al treated mice showed no impairment in spatial learning and …

… AD are oligomerization of amyloid-β peptide which is formed … environment via calcium transport
in the cell membrane. It leads to the … activation upon Aβ generation in 3xTgAD mice [102]. …

… plaques that are rich in amyloid β-peptide (Aβ), intraneuronal … protein that resides in the
plasma membrane. APP can be cleaved … Patients with AD and 3xTgAD mouse models show low …

… impairment, including amyloid angiopathy, age-related brain … genetic rescue of neuronal
NCLX in 3xTg-AD mice. At cellular level, … the possibility that not only plasma membrane, but also …

… channels on the plasma membrane, endoplasmic reticulum, … and memory impairment in
olfactory bulbectomized mice. The … homeostasis in hippocampal neurons of 3XTg-AD mice. The …

… of AD, 216 cases of mild cognitive impairment, and 864 healthy controls … This cleavage occurs
at the plasma membrane and is … The 3xTG-AD, APP-PS1ΔE9, and APPswe/PS1ΔE9 mice …

… processing to release the amyloid-β peptide, including pathogenic … roles in destroying cell
membrane integrity [10]. When the … The impairment of redox homeostasis may contribute to the …

… stage, amnestic mild cognitive impairment (MCI), exhibit high … of HNE associated with amyloid
β-peptide (Aβ) oligomers in … fibrils external to the neuronal plasma membrane. In addition, …