… changes that impair the clearance of Aβ from the brain. As Aβ … In 3xTg-AD mice, an opposing
trend is observed with … and GLUT3) to the plasma membrane and increase glucose uptake (…

… on both the amyloid-β peptide and surrounding molecules … display cognitive impairment
and hippocampal degeneration … and reduced amyloid-β and tau pathology in 3xTg AD mice […

… model of AD (3xTg-AD) were twice that found in non-transgenic animals [4]. … of the plasma
membrane channel (STIM1 or 2); and the store-operated channel in the … Aβ amyloid β peptide …

… channels on the plasma membrane, endoplasmic reticulum, … and memory impairment in
olfactory bulbectomized mice. The … homeostasis in hippocampal neurons of 3XTg-AD mice. The …

… These include the plasma membrane, the Golgi apparatus, the … Further, dendritic spines were
reduced in APP mice. Based … for impaired hippocampal learning and memory in APP mice […

… Our immunofluorescence analysis of the mouse hippocampus showed Aβ plaque formation
… HChol are also linked with cholesterol function as an important component of cell membrane …

… of excitatory pathways in brain areas such as the cerebral cortex and hippocampus. … mouse
hippocampus using immunohistochemistry and have shown they lead to severe impairment …

… ), loss of plasma membrane integrity, swelling of cytoplasmic … neuroprotective action in 3xTg
AD mice occurred by … associated with oligomeric amyloid-β peptide manifested primarily as …

… the localization of GLUT1 to the plasma membrane (55). GLUT1, … Impaired GLUTs can
set off a cascade of abnormal reactions including BBB breakdown, accelerated amyloid β -peptide …

… tau protein, and extracellular amyloid-β peptide (Aβ) plaques … Memory impairment and adult
hippocampal neurogenesis … and alterations in cognition and cerebral cortex integrity [154]. …