Vaccination of Mice with a Novel Trypsin from Trichinella spiralis Elicits the Immune Protection against Larval Challenge

Y Zhang, J Zeng, YY Song, SR Long, RD Liu, P Jiang… - Vaccines, 2020 - mdpi.com
spiralis invasion, and the major interaction location offecundity, or ADCC killing and
destruction of NBL induced by rTsT immunization, which resulted in a reduction of intestinal adults

Molecular characterization and determination of the biochemical properties of cathepsin L of Trichinella spiralis

RD Liu, XY Meng, CL Li, SR Long, J Cui, ZQ Wang - Veterinary Research, 2022 - Springer
mature TsCatL. TsCatL was transcribed and expressed in larvae and adults and located in
the stichosome, gut … hosts and is associated with worm development and female fertility [20]. …

Growth hormone stimulates the in vitro development and establishment of Haemonchus contortus in sheep

A Sánchez-Paredes, C Cuenca-Verde… - Veterinary …, 2024 - Elsevier
of hypobiotic larvae and in the increased fertility of adult … Our results on the presence and
location of possible GH-Rs … role for intestinal cells of H. contortus larvae in the recognition …

Nod-like receptor pyrin domain containing 3 plays a key role in the development of Th2 cell-mediated host defenses against Trichinella spiralis infection

X Jin, Y Yang, J Ding, X Liu, H Shi, X Luo, W Jia… - Veterinary …, 2021 - Elsevier
… The result indicated that defect of NLRP3 in mice did not affect the fecundity of adult … the
fecundity of adult worm. (A) Numbers of female adult worm and newborn larvae from intestine of

Binding of Trichinella spiralis C-type lectin with syndecan-1 on intestinal epithelial cells mediates larval invasion of intestinal epithelium

Z Wang, QQ Lu, MM Weng, YL Li, LL Han, YY Song… - Veterinary …, 2023 - Springer
… epithelium where they undergo 4 moltings to mature to adult worms (AW) at 31 h post-infection
(hpi) [6]. The male and female AW mate … The gut epithelium is the first site of T. …

Molecular cloning and characterization of a novel peptidase from Trichinella spiralis and protective immunity elicited by the peptidase in BALB/c mice

JJ Lei, YY Hu, F Liu, SW Yan, RD Liu, SR Long… - Veterinary …, 2020 - Springer
… Immunization of mice with rTsP reduced the numbers of intestinal adult worms by 38.6% …
epithelium is the primary native defence against Trichinella invasion and the principal site of

In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host's intestinal epithelial cells

J Wang, X Jin, C Li, X Chen, Y Li, M Liu… - PLOS Neglected …, 2023 - journals.plos.org
… We previously found that TsDNase II-7 is located around the infection site in the intestinal
effect of TsDNase II-7 from adult T. spiralis on IECs contributes to the invasion of the intestinal

Oral immunization of mice with recombinant Lactobacillus plantarum expressing a Trichinella spiralis galectin induces an immune protection against larval challenge

YXY Xu, XZ Zhang, MM Weng, YK Cheng, RD Liu… - Parasites & …, 2022 - Springer
of lactose alone also reduced adult worm and larval burdens and relieved partially inflammation
of intestine and muscles. … spiralis IIL, and it is also the preferential interaction location

Vaccination of mice with recombinant novel aminopeptidase P and cathepsin X alone or in combination induces protective immunity against Trichinella spiralis …

J Zeng, XZ Zhang, R Zhang, SW Yan, YY Song… - Acta Tropica, 2021 - Elsevier
Trichinella spiralis is a major foodborne zoonotic parasitic … Development of anti-Trichinella
vaccine is requisite for … effects of adult worm expulsion from the gut, female fecundity reduction…

Parasiticidal efficacy of a new formulation of silver nanoparticles on Trichinella spiralis in vitro

NM Taha, S Abdel-Radi, FS Youssef… - Journal of Advanced …, 2022 - advetresearch.com
… Exposure of Trichinella spiralis adult worms to 3, 6, 9 and 12 ppm of Ag-… After removal of
the digestive solution by … do not typically form agglomerations in one particular place (Fig. 3). …