Advances in targeted therapy for esophageal cancer

YM Yang, P Hong, WW Xu, QY He, B Li - Signal transduction and …, 2020 - nature.com
… receptor (EGFR) and vascular endothelial growth factor (VEGF), … of EGFR and HER-2, has
been approved to treat HER-2-… to mRNA through pairing, thereby inhibiting the expression

[HTML][HTML] Advances and challenges in the treatment of esophageal cancer

S He, J Xu, X Liu, Y Zhen - Acta Pharmaceutica Sinica B, 2021 - Elsevier
EGFR is overexpressed in most esophageal cancers and the … in drug resistance in the HER-2
IHC2 + /PIK3CA mutation … , use of antibodies against EGFR or VEGF ligands and oral TKIs …

CD22 is a potential target of CAR-NK cell therapy for esophageal squamous cell carcinoma

T Liu, X Dai, Y Xu, T Guan, L Hong, T Zaib… - Journal of Translational …, 2023 - Springer
… that among 10 ESCC patients, mRNA expression of CD22 in … are rare but have included
EGFR, VEGF, HER-2 and PD-L1 [17, … Based on the relationship between CD22 expression and …

A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance

A Alkrekshi, W Wang, PS Rana, V Markovic… - Cellular signalling, 2021 - Elsevier
… significant reduction in the mRNA expression level of CSC genes … -1 expression on EGFR
and HER-2 was different between breast … The NSCLC is further subdivided into squamous cell …

[HTML][HTML] E2F1/2/4 mRNA is associated with immune infiltration and are potential biomarkers for the prognosis of human gastric carcinoma

Y Chen, W Gong, W Dai, H Jiang… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
… (HER-2), vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR
in pancreatic ductal adenocarcinoma and esophageal squamous cell carcinoma (15). E2F1 …

Advances in the Theranostics of Oesophageal Squamous Carcinoma

M Cheng, Q Xin, S Ma, M Ge, F Wang… - Advanced …, 2023 - Wiley Online Library
… Lapatinib, a small-molecule inhibitor of EGFR and HER-2, … and survival by targeting mRNAs
for cleavage or translational … esophageal squamous cell carcinoma using Fluorescence in …

Expression and function analysis of CRABP2 and FABP5, and their ratio in esophageal squamous cell carcinoma

M Li, C Li, P Lu, B Wang, Y Gao, W Liu, Y Shi, Y Ma - Open Medicine, 2021 - degruyter.com
… of esophageal cancer for known targets like EGFR and HER-2 … compared the expression
levels of CRABP2 mRNA in 286 … , and reduce the expression of ERK/VEGF pathway-related …

Identification of a Prognostic Gene Signature Based on Lipid Metabolism-Related Genes in Esophageal Squamous Cell Carcinoma

GY Shen, PJ Yang, WS Zhang, JB Chen… - Pharmacogenomics …, 2023 - Taylor & Francis
… We downloaded the mRNA expression … (EGFR) and vascular endothelial growth factor
(VEGF), respectively. Trastuzumab, an anti-human epidermal growth factor receptor 2 (HER-2) …

[HTML][HTML] Tumor Cell-Derived Complement Component C1r Acts as a Prognostic Biomarker and Promotes Esophageal Squamous Cell Carcinoma Progression

M Tang, S Zhao, L Ren, Q Li, L Li, C Wang… - Frontiers in Bioscience …, 2024 - imrpress.com
EGFR), human epidermal growth factor receptor 2 (HER-2), or vascular endothelial growth
factor (VEGF… ) and the prognostic value of C1R mRNA was assessed using the Survfit function …

Cancer-associated fibroblasts: An emerging target against esophageal squamous cell carcinoma

L Qiu, J Yue, L Ding, Z Yin, K Zhang, H Zhang - Cancer letters, 2022 - Elsevier
… Moreover, EGFR-, HER-2-, or VEGF-targeted therapy does … Several studies have
established a link between CAFs and … They found that hsa-miR-3656 mRNA expression was …