HER Receptor, Current, and Emerging Therapeutic Targets

ML Tan, JW Yeap, A Matawali - Handbook of Cancer and Immunology, 2023 - Springer
… line treatment for HER-2positive esophageal adenocarcinoma, not … the activity of EGFR/HER-1
and HER-2 and downstream … Hence, based on the relationship between HER-2 and PI3K, …

[PDF][PDF] … of HIF-1α and high density of tumor associated macrophages predict tumor aggression, invasion and unfavorable prognosis of Kazakh esophageal squamous …

Y Xie, X Jiang, C Jiang, X Yuan, X Wang, L Yang, C Liu… - 2020 - scholar.archive.org
… The relationship between the expression of VEGF, EGFR, and HER-2 mRNA in esophageal
squamous cell carcinoma (ESCC) and clinicopathological features of different ethnic groups …

[HTML][HTML] Progress on the effects and underlying mechanisms of evodiamine in digestive system diseases, and its toxicity: A systematic review and meta-analysis.

Z Zhou, Y Zhou, Z Zhang, M Zhao, C Hu, L Yang… - Phytomedicine, 2024 - Elsevier
… cancer, tongue squamous cancer, hepatitis B, oral cancer, and esophageal cancer in vivo. …
EVO may induce apoptosis through the EGFR, PI3K-AKT, and p53 signaling pathways in …

Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis

SD Luo, HT Tsai, CF Hwang, TJ Chiu, SH Li… - Journal of Experimental …, 2022 - Springer
… epithelial ovarian, esophageal squamous cell carcinoma and … We systematically analyzed
the correlation between leptin … the mRNA level of leptin was positively correlated with mRNA

Capsaicin: A chili pepper bioactive phytocompound with a potential role in suppressing cancer development and progression

A Mondal, S Banerjee, W Terang… - Phytotherapy …, 2024 - Wiley Online Library
… kinase 2 (CHK2) mRNA expression levels and reduced the … As a result, capsaicin has
blocked the EGFR/HER-2 signal … effect against esophageal squamous cell carcinoma (ESCC) …

[HTML][HTML] Reassessing vascular endothelial growth factor (VEGF) in anti-angiogenic cancer therapy

TC Elebiyo, D Rotimi, IO Evbuomwan… - Cancer Treatment and …, 2022 - Elsevier
… The increased expression of VEGF mRNA has been … [79] showed that the flavone, apigenin,
inhibited esophageal … overexpression of VEGF and its receptors, HIF-, angiopoietin-1, EGFR, …

Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

P Asgharian, AP Tazekand, K Hosseini… - Cancer cell …, 2022 - Springer
… When it comes to HER-2-expressing breast cancer, this … the advancement of esophageal
squamous cell carcinoma in a … regulating the expression of cleaved-caspase-3 and EGFR can …

Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics

A Chamoli, AS Gosavi, UP Shirwadkar, KV Wangdale… - Oral oncology, 2021 - Elsevier
EGFR allows the oral squamous cells to undergo epithelial-… a relationship between the
overexpression of EGFR, HER2, … (EGF) or vascular endothelial growth factor (VEGF) that activates …

[HTML][HTML] Recent progress on FAK inhibitors with dual targeting capabilities for cancer treatment

X Wu, J Wang, Q Liang, R Tong, J Huang… - Biomedicine & …, 2022 - Elsevier
… , PI3K, and EGFR/HER-2, that provide survival … esophageal squamous cell carcinoma via
EGFR/FAK inhibition pathway [110]. Consequently, simultaneous combined inhibition of EGFR/…

Resistance to Targeted Therapy in Breast Cancer

M Bida, B Mosoane, Z Mbita, D Demetriou… - … to Precision and AI …, 2024 - Springer
… AhR mRNA overexpression in BC makes it a viable treatment … HER-2 in contrast to other
members of the EGFR tyrosine … In human BC, the expression of VEGF serves as a prognostic …