Restless legs syndrome

M Manconi, D Garcia-Borreguero… - Nature reviews Disease …, 2021 - nature.com
The primary pathology of restless legs syndrome (RLS) may relate to brain iron deficiency
that might induce hyperdopaminergic and hyperglutamatergic states. Such interplay between …

The management of restless legs syndrome: an updated algorithm

MH Silber, MJ Buchfuhrer, CJ Earley, BB Koo… - Mayo Clinic …, 2021 - Elsevier
Restless legs syndrome (RLS) is characterized by an urge to move the legs, usually in …
responsible use for refractory restless legs have been developed 17 ; the use of intravenous iron …

[HTML][HTML] Restless legs syndrome: contemporary diagnosis and treatment

TR Gossard, LM Trotti, A Videnovic, EK St Louis - Neurotherapeutics, 2021 - Elsevier
The severity of impairment from RLS is commonly measured subjectively by rating scales
such as the International Restless Legs Syndrome Study Group rating scale (IRLS) or its self-…

Restless legs syndrome: An overview of pathophysiology, comorbidities and therapeutic approaches

A Vlasie, SC Trifu, C Lupuleac… - Experimental and …, 2022 - spandidos-publications.com
… pathophysiology, common comorbidities and current therapeutic modalities in the
treatment/management of restless legs syndrome (RLS) a sensorimotor neurological disorder. …

Worldwide estimation of restless legs syndrome: a systematic review and meta‐analysis of prevalence in the general adult population

A Broström, Z Alimoradi, J Lind… - Journal of Sleep …, 2023 - Wiley Online Library
… -regression assessed the prevalence of restless legs syndrome (RLS) in the general adult
… data regarding the prevalence of RLS. The protocol was pre-registered in the International …

Exploration of restless legs syndrome under the new concept: A review

Z Liu, R Guan, L Pan - Medicine, 2022 - journals.lww.com
Restless leg syndrome (Restless legs syndrome, RLS) is a common neurological disorder.
The … recent pathophysiological developments have shown the contribution of various genetic …

Restless legs syndrome across the lifespan: symptoms, pathophysiology, management and daily life impact of the different patterns of disease presentation

G Didato, R Di Giacomo, GJ Rosa, A Dominese… - International Journal of …, 2020 - mdpi.com
Restless legs syndrome is a common but still … by peculiar symptoms typically occurring in
the evening and at night, … The diagnosis of restless legs syndrome can be challenging in some …

Restless legs syndrome: known knowns and known unknowns

E Antelmi, L Rocchi, A Latorre, D Belvisi, F Magrinelli… - Brain Sciences, 2022 - mdpi.com
Restless legs syndrome (RLS) is a common neurological disorder affecting up to 15% of the
general population [1,2,3]. It is categorized as a sleep-related movement disorder (MD) due …

Brain-iron deficiency models of restless legs syndrome

CJ Earley, BC Jones, S Ferré - Experimental neurology, 2022 - Elsevier
… In this review, we present the current research on dopaminergic changes … in the BID rodent
model to provide a validation of the BID rodent model. We also demonstrate the ability of the

Attention deficit hyperactivity disorder and restless leg syndrome across the lifespan: A systematic review and meta-analysis

DP Migueis, MC Lopes, E Casella, PV Soares… - Sleep medicine …, 2023 - Elsevier
the association between attention deficit hyperactivity disorder (ADHD) and restless legs
syndrome (RLS) in accordance with the … evaluated the quality of the articles using the National …