Molecular mechanisms of Neuroprotection after the intermittent exposures of Hypercapnic Hypoxia

PP Tregub, VP Kulikov, I Ibrahimli, OF Tregub… - International Journal of …, 2024 - mdpi.com
… cyto- and neuroprotection [83] The importance of HSP-70 in … cytoprotection and the
neuroprotective properties of its high … role of VEGF, HSP-70 and protein S-100B in the potentiation

[HTML][HTML] Hamartin: An endogenous neuroprotective molecule induced by hypoxic preconditioning

S Li, C Ren, C Stone, A Chandra, J Xu, N Li… - Frontiers in …, 2020 - frontiersin.org
… Endogenous neuroprotective molecules such as VEGF and HIF-1 are induced by IPC/HPC,
whereupon they act to increase neuronal tolerance to hypoxia/ischemia. Therefore, …

[HTML][HTML] Relationship between Hypoxia and Hypercapnia Tolerance and Life Expectancy

PP Tregub, YK Komleva, VP Kulikov… - International Journal of …, 2024 - mdpi.com
… the effect of the mutual potentiation of the protective effects of … mediated by increased levels
of VEGF in the body [52]. At the … have both neuroprotective and neurotoxic effects depending …

Neuroprotective effect of hypoxic-hypercapnic training. Review

D Tolstun, V Kholin - Ageing and longevity, 2023 - aging-longevity.org.ua
… , AI; Belousov, AA; The role of VEGF, HSP 70 and protein S 100B in the mechanisms of
hypercapnia potentiation of the neuroprotective effect of hypoxia. Pathological physiology and …

Therapeutic hypercapnia. Review

D Tolstun, K Muradian, V Bezrukov - Ageing and longevity, 2022 - aging-longevity.org.ua
… , AI; Belousov, AA The role of VEGF, HSP 70, and protein S 100B in the mechanisms of
hypercapnia potentiation of the neuroprotective effect of hypoxia. Pathological physiology and …

[HTML][HTML] Fluid biomarkers of neuro-glial injury in human status epilepticus: a systematic review

G Giovannini, S Meletti - International Journal of Molecular Sciences, 2023 - mdpi.com
… be crucial in promoting neuroprotective strategies in addition … active part in long-term
potentiation in the hippocampus. Nfs … of NfH and heat shock protein 70 (HSP-70) within 48 h after …

Hypercapnia potentiates HIF-1α activation in the brain of rats exposed to intermittent hypoxia

PP Tregub, NA Malinovskaya, AV Morgun… - Respiratory Physiology …, 2020 - Elsevier
… interpret our results as the possible potential for neuroprotection. The assessment of HIF-1α …
demonstrated that hypercapnia had a potentiating effect when accompanied by hypoxia. …

Hypercapnia Modulates the Activity of Adenosine A1 Receptors and mitoK+ATP-Channels in Rat Brain When Exposed to Intermittent Hypoxia

PP Tregub, NA Malinovskaya, ED Osipova… - NeuroMolecular …, 2022 - Springer
… of the neuroprotective effects of hypercapnia and its combination with hypoxia are not studied
sufficiently. The study aims to test the hypothesis of the potentiating effect of hypercapnia …

[HTML][HTML] Skin/muscle incision and retraction regulates the persistent postoperative pain in rats by the Epac1/PKC-βII pathway

J Qian, X Lin, Z Zhou - BMC anesthesiology, 2022 - Springer
… , VEGF, PGP9.5 proteins and the decrease of EPO protein in … , exerting anti-inflammatory
and neuroprotective effects [39], … , VEGF, PGP9.5 protein levels, and decreased EPO protein

[HTML][HTML] Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases

A Sen - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
… mechanisms of the neuroprotection provided by OA and its … (GSK-3β) suggesting that EsA
potentiates the NRF-2-controlled … resulted from the downregulation of the VEGF/ pFAK/pJNK/…